31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
29 citations
,
October 2020 in “Journal of the European Academy of Dermatology and Venereology” This article is a discussion piece that examines the clinical symptoms of hyperandrogenic women with COVID-19, without reporting new research findings.
28 citations
,
January 2003 in “Urologic oncology” This review discusses the hormonal influences on prostate carcinogenesis and notes ongoing trials investigating whether finasteride could reduce prostate cancer incidence by inhibiting dihydrotestosterone synthesis, but it reports no new results.
27 citations
,
April 2005 in “Journal of Chemotherapy” This study reported two cases of alopecia universalis triggered by PEG-interferon and ribavirin therapy for chronic hepatitis C, with hair regrowth observed after therapy completion or withdrawal.
26 citations
,
January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
25 citations
,
June 2019 in “Endocrine Related Cancer” This review discusses the structure and function of steroid nuclear receptors, particularly focusing on androgen receptor dysregulation in prostate cancer and androgen insensitivity syndromes, without reporting new experimental results.
22 citations
,
August 2011 in “Endocrine Practice” This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.
21 citations
,
November 2018 in “Journal of Psychosomatic Obstetrics & Gynecology” This study found that women with PCOS exhibited higher levels of alexithymia and body uneasiness compared to healthy controls, affecting their psychological and social well-being.
21 citations
,
March 2018 in “Experimental Dermatology” This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.
20 citations
,
December 2000 in “Fertility and Sterility” This study found that the N363S variant of the glucocorticoid receptor was rare among women with PCOS and did not significantly contribute to genetic risk for PCOS or adrenal androgen excess.
18 citations
,
May 2020 in “Biomolecules” This review discusses spironolactone's new roles in tumor immunosurveillance, DNA repair inhibition, and viral infection suppression, highlighting its potential to extend uses beyond traditional applications, but reports no clinical results.
18 citations
,
March 2009 in “Medical Hypotheses” This review discusses the potential link between long-term transdermal exposure to sex hormones from antiperspirants and increased breast and prostate cancer rates, calling for further research to confirm this theory.
17 citations
,
August 2019 in “Archives of Cardiovascular Diseases” In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.
17 citations
,
February 2019 in “Journal of Clinical Medicine” This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.
17 citations
,
February 2011 in “Expert Opinion on Drug Safety” This review discusses adverse effects associated with pegylated IFN therapy for chronic hepatitis C and highlights the potential of new antiviral drugs to reduce side effects and improve treatment adherence, but reports no new clinical results.
16 citations
,
January 2023 in “Cureus” This article discusses the characteristics and potential consequences of polycystic ovarian syndrome, including its effects on fertility and risk for other health conditions, but it reports no new findings.
16 citations
,
June 2008 in “Springer eBooks” Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
16 citations
,
January 1980 in “Planta Medica” This study found that alcoholic extracts of Cinchona succirubra, Dictamnus dasycarpus, Brassica juncea, and Sophora flavescens promoted hair growth in 5-week-old mice.
15 citations
,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
14 citations
,
December 2010 in “Seminars in Oncology” This review discusses the diagnostic challenges of androgen and estrogen-secreting adrenal tumors and highlights that the presence of metastases is the most reliable indicator of malignancy; it reports no new clinical findings.
14 citations
,
July 1987 in “Dermatologic Clinics” This article reviews current evaluation and treatment options for androgenic alopecia in women and reports no new clinical results.
12 citations
,
March 2015 in “Pediatric Dermatology” This review discusses diagnostic and management challenges of polycystic ovary syndrome in children and adolescents and reports no new clinical results; it emphasizes early intervention when a provisional diagnosis is suspected.
11 citations
,
August 2019 in “The Journal of Sexual Medicine” This study found that women with nonclassic congenital adrenal hyperplasia (NC-CAH) reported lower sexual function and higher sexual distress compared to those with classic CAH (C-CAH), particularly among those showing signs of androgen excess.
11 citations
,
November 2017 in “Electronic physician” In this study, no significant correlation was found between depression scores and body mass index, HOMA-IR, or testosterone levels in women with or without polycystic ovary syndrome.
11 citations
,
July 2012 in “Current Opinion in Pediatrics” This review discusses dermatologic signs in childhood endocrine disorders and highlights their importance in early diagnosis and treatment, but it reports no new clinical findings.
10 citations
,
January 2018 in “Seminars in Reproductive Medicine” This review discusses the challenges in diagnosing and managing polycystic ovary syndrome and highlights the need for an integrated, multidisciplinary healthcare model tailored to the diverse needs of women with PCOS; it reports no new clinical findings.
10 citations
,
May 2009 in “Sexual and Relationship Therapy” This review summarizes existing clinical guidelines for hormonal therapy in gender dysphoria, observing similarities in international practices and emphasizing the need for more evidence-based research, particularly on GnRH agonists for both trans women and men.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.
10 citations
,
January 2003 in “Seminars in reproductive medicine” This review covers the pathophysiology, diagnosis, evaluation, and treatment of hirsutism and reports no new clinical findings.