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    Glossary Down syndrome

    genetic disorder caused by an extra copy of chromosome 21

    Down syndrome, also known as Trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21. This condition leads to developmental delays, characteristic facial features, and often, various health issues such as heart defects and thyroid problems.

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    1. Janus kinase inhibition in Down syndrome: 2 cases of therapeutic benefit for alopecia areata JAAD case reports · 2019 · 32 citations
    2. Alopecia areata in Down syndrome: a clinical evaluation Journal of the European Academy of Dermatology and Venereology · 2005 · 22 citations
    3. Down Syndrome and Autoimmune Disease Clinical Reviews in Allergy & Immunology · 2024 · 14 citations
    4. Dermatological aspects of the S2k guidelines on Down syndrome in childhood and adolescence JDDG Journal der Deutschen Dermatologischen Gesellschaft · 2018 · 10 citations
    5. Immunological Profile of Patients Presenting Down Syndrome and Alopecia Areata Advanced techniques in biology & medicine · 2015 · 1 citations
    6. A Case of Alopecia Areata with Gluten Intolerance in a Child with Down Syndrome: A Homeopathic Perspective Medico Research Chronicles · 2026
    7. Treatment of Alopecia Universalis in a Child with Down Syndrome 2023
    8. Common Dermatologic Disorders in Down Syndrome: Systematic Review (Preprint) 2021
    9. Alopecia areata and Down syndrome: A true association and the importance of dermoscopic diagnosis Journal of The American Academy of Dermatology · 2016
    10. Letter To Editor-Alopecia universalis in Down syndrome: Response totherapy TSpace · 2007
    11. Eruptive syringomas in Down’s syndrome Nasza Dermatologia Online · 2018
    12. Dermatological Manifestations of Down's Syndrome Journal of cutaneous medicine and surgery · 2001 · 28 citations
    13. JAK inhibition decreases the autoimmune burden in Down syndrome eLife · 2024 · 18 citations
    14. Common Dermatologic Disorders in Down Syndrome: Systematic Review JMIR Dermatology · 2022 · 10 citations
    15. JAK inhibition decreases the autoimmune burden in Down syndrome eLife · 2024 · 2 citations
    16. LB943 Tofacitinib treatment of inflammatory skin conditions in patients with Down Syndrome 2022 · 1 citations
    17. JAK Inhibitors in Down Syndrome: Alopecia Areata Resolution and Vitiligo Improvement with Baricitinib Acta Dermato Venereologica · 2025
    18. A Case of Alopecia Areata with Gluten Intolerance in a Child with Down Syndrome: A Homeopathic Perspective Medico Research Chronicles · 2026
    19. Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome Research Square (Research Square) · 2023
    20. Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial Translational Psychiatry · 2012 · 81 citations
    21. Rheumatoid arthritis and gouty arthritis in an adult patient with Down's syndrome 2020
    22. COMPARATIVE ANALYSIS OF MAJOR AND TRACE ELEMENT CONTENT IN THE HAIR OF CHILDREN WITH DOWN SYNDROME AND OBESITY Trace Elements in Medicine (Moscow) · 2019
    23. Alopecia universalis and Kallman’s Syndrome Dermatology · 1986 · 2 citations
    24. The pattern and profile of alopecia areata in Singapore – a study of 219 Asians International Journal of Dermatology · 2002 · 275 citations
    25. THE PATHOGENESIS OF ALOPECIA AREATA Dermatologic Clinics · 1996 · 89 citations
    26. Temporal triangular alopecia and a review of 52 past cases Journal of Dermatology · 2010 · 56 citations
    27. Prevalence, comorbidities, and treatment patterns of Japanese patients with alopecia areata: A descriptive study using Japan medical data center claims database The Journal of Dermatology · 2022 · 35 citations
    28. Screening Guidelines for Thyroid Function in Children With Alopecia Areata JAMA dermatology · 2017 · 35 citations
    29. Clinical and trichoscopic characteristics of temporal triangular alopecia: A multicenter study Journal of the American Academy of Dermatology · 2016 · 32 citations
    30. Screening guidelines for thyroid function in children with alopecia areata Journal of The American Academy of Dermatology · 2018