39 citations
,
January 2012 in “Acta dermato-venereologica” This study examined 27 DRESS patients diagnosed in Thailand, identifying phenytoin, allopurinol, and nevirapine as common causes, with a 3.7% mortality rate and systemic corticosteroids being a common treatment.
37 citations
,
April 2012 in “British Journal of Dermatology” This study found that among middle-aged Korean women, those with metabolic syndrome had a higher risk of androgenetic alopecia, while no significant association was observed in men.
37 citations
,
December 2003 in “Reproductive Toxicology” The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.
36 citations
,
October 2016 in “Medical mycology” This study at Mbarara University of Science and Technology found that T. violaceum is the most common cause of tinea capitis in children in Western Uganda, and systemic therapy is preferred over topical treatments for effective management due to the nature of the infection.
36 citations
,
January 2015 in “Clinical and Translational Allergy” This review discusses allergic reactions to pollen in dogs, cats, and horses and suggests that these animals' spontaneous allergies could serve as models for translational clinical studies applicable to human allergies.
35 citations
,
January 2019 in “Clinics in Dermatology” This review discusses contemporary issues in syphilis diagnosis and management, emphasizing the importance of recognizing and addressing both biomedical and psychosocial aspects, but provides no new clinical results.
35 citations
,
October 2017 in “JAMA dermatology” This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.
34 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study estimates the prevalence of hyperandrogenic states in late adolescent and young females, revealing that these disorders often begin at a young age.
34 citations
,
July 2011 in “Journal of the European Academy of Dermatology and Venereology” This study identified distinct dermoscopic patterns associated with different types of scalp tumors, highlighting variability in lesions related to patient age, gender, and tumor thickness.
33 citations
,
May 2015 in “JAMA Dermatology” This study identifies comedonal or cystic fibrofolliculomas as novel diagnostic clues for earlier recognition of Birt-Hogg-Dube syndrome, potentially facilitating timely surveillance of associated systemic complications.
33 citations
,
January 2009 in “Journal of Cutaneous and Aesthetic Surgery” This study found no clear evidence that finasteride negatively affects erectile function, though it does cause a reduction in ejaculatory volume and has potential implications for prostate cancer risk.
30 citations
,
January 2024 This review explores and updates previous findings on the skin manifestations associated with diabetes, questioning some established signs while introducing additional cutaneous symptoms linked to the condition.
30 citations
,
July 2023 in “Clinical Chemistry and Laboratory Medicine (CCLM)” In this study, researchers developed an LC-MS/MS method to accurately quantify cortisone and cortisol levels in human scalp hair, finding that concentrations decrease predictably along the hair shaft, which could assist in identifying abnormal glucocorticoid exposure.
28 citations
,
January 2012 in “Case Reports in Medicine” This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
28 citations
,
August 2009 in “Nursing for Women's Health” This review highlights that while healthcare providers are starting to diagnose polycystic ovary syndrome earlier in teens, the psychological and social needs often remain inadequately addressed.
28 citations
,
January 2009 in “Journal of Cutaneous and Aesthetic Surgery” This article discusses Serenoa repens for androgenetic alopecia and reports no strong evidence of its effectiveness, emphasizing the need for larger clinical trials.
27 citations
,
November 2020 in “International Journal of Dermatology” This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.
27 citations
,
August 2008 in “Mayo Clinic proceedings” This review discusses the diagnosis, management, and treatment options for peripheral arterial disease and does not report new clinical findings; the authors emphasize the need for early diagnosis and comprehensive management.
26 citations
,
December 2009 in “Laser Physics” This study observed that caffeine-containing shampoo can penetrate hair follicles to a depth of approximately 200 μm and remains detectable even after 24 hours, suggesting a potential long-term reservoir effect.
25 citations
,
January 2013 in “Colloids and surfaces. B, Biointerfaces” This study found that melanin granules in black human hair are key dyeing regions for oxidative hair coloring, as confirmed by nanoscale mass spectrometry analysis detecting deuterium ions.
24 citations
,
January 2015 in “International Journal of Trichology” This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.
23 citations
,
June 2016 in “Journal of Veterinary Internal Medicine” This case series reports three cats diagnosed with hypersomatotropism due to GH-secreting pituitary adenomas without concurrent diabetes mellitus, highlighting the potential for underdiagnosis in non-diabetic cats.
23 citations
,
November 2011 in “Journal of the European Academy of Dermatology and Venereology” This study observed that in pemphigus vulgaris patients, hair loss and alopecic patches may result from anti-desmoglein autoantibody-mediated acantholysis and inflammatory changes, leading to non-scarring alopecia with potential for regrowth after treatment.
23 citations
,
January 2008 in “Skin Pharmacology and Physiology” This study demonstrated that optical coherence tomography effectively detects significant changes in hair structure caused by steroid treatment, suggesting its potential use in doping control and clinical therapy monitoring.
23 citations
,
April 2006 in “Skin Research and Technology” This study observed that hair density and growth rates vary by location and age, and the presence of thin hairs predominates in younger women with mild patterned hair loss.
22 citations
,
January 2012 in “Obstetrics and Gynecology International” In this study of Bulgarian women, the waist-to-stature ratio was a better marker for an unfavorable metabolic profile than the waist-to-hip ratio among those with PCOS and obesity.
21 citations
,
June 2016 in “Reproductive Sciences” This study found increased IL-18 levels in the endometrium of women with polycystic ovary syndrome, especially in those who are overweight, suggesting a link with body mass index.
21 citations
,
January 2010 in “International Journal of Trichology” This study concluded that TrichoScan is error-prone in its current form and overestimates certain hair growth parameters, with results not aligning with clinical severity of alopecia.
20 citations
,
December 2015 in “Der Urologe” Combining medications is more effective for treating benign prostatic syndrome symptoms.
19 citations
,
July 2005 in “Steroids” In this study, researchers developed a sensitive LC–MS–MS assay to measure 3α-androstanediol levels in rat plasma and observed that testosterone raises these levels via a 5α-reductase pathway.