Optical Coherent Tomography for In Vivo Determination of Changes in Hair Cross Section and Diameter During Treatment with Glucocorticosteroids: A Simple Method to Screen for Doping Substances?

    January 2008 in “ Skin Pharmacology and Physiology
    Jürgen Lademann, J. Shevtsova, Alexa Patzelt, Heike Richter, N.D. Gladkowa, Valentin M. Gelikonov, С. А. Гончуков, Wolfram Sterry, A. Sergeev, Ulrike Blume‐Peytavi
    TLDR Optical coherent tomography can effectively detect steroid use by analyzing hair changes.
    The study utilized optical coherent tomography to analyze changes in hair structure during steroid treatment for patients with autoimmune diseases. It found significant differences in hair cross-section, though the hair shape remained unchanged. This non-invasive, low-cost method proved effective for doping control, allowing only athletes with abnormal hair parameters to undergo further testing. The findings were relevant not only for doping detection but also for clinical applications, such as monitoring therapy and compliance when substances affect hair structure.
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