1 citations
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January 2004 in “Cosmetics and toiletries” Polyquaternium-64 helps damaged hair look healthy again.
2 citations
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December 1994 in “International Journal of Cosmetic Science” In this study, the combination of biologically engineered hyaluronic acid and polyquaternium-10 improved hyaluronic acid's retention and moisturizing effects on hair by forming a stable complex that increased binding affinity to keratin.
8 citations
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December 2003 in “Materials Research-ibero-american Journal of Materials” Polyquaternium 7® builds up on hair, improving its look and feel, and AFM is good for measuring these changes.
January 2002 in “China Surfactant Detergent & Cosmetics” This study compared shampoos and found that shampoo D, containing polyquaternium-10, guar gum, and dimethicone, was most effective in restoring chemically permed hair.
2 citations
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January 2004 in “PubMed” This study concluded that Polyquaternium-10 conditioner softens the surface of the scale face on hair fibers.
4 citations
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November 2017 in “Journal of Cosmetic Dermatology” This study found that polyquaternium-68 at pH 9 achieved the greatest hair deposition, while polyquaternium-44 demonstrated the best wash resistance at pH 6.
December 2014 in “Nicolaus Copernicus University Repository (Nicolaus Copernicus University)” In this study, UV-light at 254 nm and Polyquaternium-7 treatment were found to affect the mechanical properties and surface structure of hair.
42 citations
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January 2009 in “Colloids and Surfaces B: Biointerfaces” This study found that dimethylpabamidopropyl laurdimonium tosylate, a quaternary ammonium surfactant, adsorbs onto human scalp hair with kinetic and isotherm behaviors fitting specific models, changing hair fiber wettability from hydrophobic to hydrophilic.
March 2011 in “Focus on surfactants” Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.
August 2018 in “Biomedical Journal of Scientific & Technical Research” This study found that covalently binding antimicrobial agents to hair shafts provided antibacterial activity against dandruff and odor-associated bacteria, which remained effective even after several washes.
April 2025 in “BMC Chemistry” This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.
March 2019 in “Reactions Weekly” 1 citations
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January 2004 in “China Surfactant Detergent & Cosmetics” This study found that tea-seed saponin modified silicone polymer quaternary ammonium salt significantly improves hair conditioning performance in both dry and wet states when used in shampoo formulations.
31 citations
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February 1972 in “Experientia” This study found that the diphosphonate ethan-1-hydroxy-1,1-diphosphonat was the most effective compound in preventing calcifications in rats induced by DHT, compared to other phosphatase inhibitors and polyphosphates tested.
January 2010 in “EPub Bayreuth (University of Bayreuth)” This study found that Polyquaternium-87 significantly reduced friction forces on hair surfaces treated with various shampoo formulations, highlighting its potential for improving hair care products.
January 2023 in “Minds at UW (University of Wisconsin)” This study suggests that while DI water significantly impacts hair, the effects of citric acid, hydrogen peroxide, and sodium chloride in shampoo on hair remain unclear, requiring further investigation.
December 2023 in “The journal of physical chemistry. B (1997 : Online)” This study explored the potential of human hair keratin as a filtration material, finding that it may effectively absorb the pollutants diclofenac and perfluorobutanesulfonate. The researchers reported significant binding affinities through molecular simulations, supporting further investigation into keratin's use for water purification.
January 2013 in “Transactions of the Materials Research Society of Japan” In this study, carboxymethylalanyl disulfide keratin was shown to effectively prevent hair damage during repeated bleaching and permanent waving treatments.
16 citations
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October 2003 in “Journal of applied polymer science” This study found that chemically modifying hair with 2-iminothiorane hydrochloride improved the permanence of hair setting without damaging the hair by increasing disulfide bonds.
3 citations
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January 1989 in “Journal of Japan Oil Chemists Society” This study examined the effects of six surfactants on hair and scalp, finding varying irritation levels and impacts on protein denaturation and scalp turnover time, with AMT suggested as a good detergent.
March 2023 in “Reactions Weekly” 10 citations
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February 2018 in “Royal Society Open Science” This study found that a shampoo containing quaternized wheat protein hydrolysate can effectively improve hair recovery by smoothing and compacting damaged hair surfaces, thanks to modifications that enhance protein adherence and disulfide bond formation at pH levels typical in hair care products.
2 citations
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August 2023 in “Molecules” This study found that a quinazoline derivative, SH-340, increased skin barrier-associated factors and inhibited TSLP expression and STAT6 phosphorylation in human primary keratinocytes, suggesting potential benefits for alleviating inflammation and improving skin barrier function in atopic dermatitis.
July 2026 in “Preprints.org” In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
3 citations
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January 1985 in “Drug development and industrial pharmacy” In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.
5 citations
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January 2011 in “International Journal of Cosmetic Science” This study found that 1,2,3,4-tetrahydroquinoline derivatives, particularly N-methyl-7-amino-1,2,3,4-tetrahydroquinoline, may be excellent blue dye candidates for human hair, offering superior color purity, stability, and fastness compared to 2,3-dihydroindoles.
November 2004 in “Qucosa (Saxon State and University Library Dresden)” This study developed analytical methods to better understand hair treatment with cosmetic formulations, revealing that active agents primarily adsorb on the hair surface during short washes.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.
4 citations
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January 1988 in “Cosmetics and toiletries” 0.1% piroctone olamine in hair tonics effectively treats dandruff.
December 2022 in “Research journal of topical and cosmetic sciences” This study evaluated a herbal anti-dandruff hair wash powder, TRICHONEMTM, composed of eighteen herbal ingredients, reporting effective in vitro anti-dandruff activity and high user satisfaction in a 4-week pilot trial involving 50 women, without causing irritation.