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Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Estrogen therapy helped regrow hair in a bald man.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Healthcare providers need better education and policies to serve transgender individuals effectively.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Autoimmune polyglandular syndrome can cause temporary brain issues that may improve on their own.

Follicular unit extraction is an effective hair transplant method for advanced baldness with high patient satisfaction, but some experienced decreased density over time.

Most women aged 20-40 in the study lost hair diffusely and in volume over 6 weeks to 6 months, mainly due to telogen effluvium, often without a clear cause.

Dermatologists can help detect and manage eating disorders by recognizing skin changes.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Finasteride improves hair growth and satisfaction in men with male pattern baldness but may cause sexual side effects.

High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.