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Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Sulforaphane from broccoli can help protect skin from sun damage.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

New effective scar treatments are urgently needed due to the current options' limited success.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Stem cell niches support, regulate, and coordinate stem cell functions.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.