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    Glossary Cortical Cells

    specialized hair cells providing strength, color, and texture

    Cortical cells are specialized cells found in the cortex of the hair shaft, which is the thickest layer of the hair. These cells are responsible for providing strength, color, and texture to the hair by containing keratin and melanin. For professionals, understanding the structure and function of cortical cells is crucial for diagnosing and treating hair disorders such as alopecia.

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    1. Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. 1986 · 356 citations
    2. Cortical cell types and intermediate filament arrangements correlate with fiber curvature in Japanese human hair Journal of structural biology · 2008 · 62 citations
    3. Upcycling waste hair and feathers derived keratin into intact cortical cell-derived micro-units via periodate oxidation: Applications & life cycle assessment International Journal of Biological Macromolecules · 2026
    4. Stiffness of Human Hair Correlates with the Fractions of Cortical Cell Types Cosmetics · 2019 · 4 citations
    5. Prenatal transplantation of epidermal neural crest stem cells in malformation of cortical development mouse model Microscopy Research and Technique · 2016 · 5 citations
    6. Protein-phosphatase inhibitors block root hair growth and alter cortical cell shape of Arabidopsis roots Planta · 1994 · 61 citations
    7. The cell membrane complex: Three related but different cellular cohesion components of mammalian hair fibers International Journal of Cosmetic Science · 2010 · 15 citations
    8. Mechanism research of yak hair stretching slenderization based on the changes of conformation and cell shape 2009
    9. In vitro Growth and Differentiation of Epithelial Cells derived from Post-embryonic Hair Follicles Australian Journal of Biological Sciences · 1982 · 7 citations
    10. Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    11. Angelica sinensis promotes cortical regeneration of the thymus in mice with acute thymic involution induced by short-term rapamycin treatment Journal of Zhejiang University (Medical Sciences) · 2026
    12. Gene Expression of Mouse S100A3, a Cysteine-Rich Calcium-Binding Protein, in Developing Hair Follicle 1998 · 40 citations
    13. Monilethrix: an ultrastructural study Journal of Cutaneous Pathology · 1984 · 34 citations
    14. Fractography of human hair Journal of applied polymer science · 1982 · 34 citations
    15. Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair Journal of Investigative Dermatology · 2009 · 34 citations
    16. Cosmetic assessment of the human hair by confocal microscopy Scanning · 2002 · 25 citations
    17. Isolation and Characterization of a Novel Hair Follicle–Specific Gene, Hacl-1 Journal of Investigative Dermatology · 1994 · 25 citations
    18. Isolation and Characterization of Mouse High-glycine/Tyrosine Proteins Journal of Biological Chemistry · 1997 · 24 citations
    19. The structure of hair and follicles of mice carrying the naked (<i>N</i>) gene Genetics Research · 1982 · 21 citations
    20. Bubble hair Journal of cutaneous pathology · 1992 · 16 citations
    21. Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma Experimental Dermatology · 1997 · 8 citations
    22. Ultrastructural immunolocalization of involucrin in the medulla and inner root sheath of the human hair Annals of anatomy · 2011 · 7 citations
    23. Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets. 1996 · 6 citations
    24. Characterization of nonkeratinous proteins extracted from human hair by permanet wave lotion. Journal of Society of Cosmetic Chemists of Japan · 1990 · 5 citations
    25. Morphology and Properties of Hair Routledge eBooks · 2018 · 3 citations
    26. The Secrets of Beautiful Hair: Why is it Flexible and Elastic? Cosmetics · 2019 · 2 citations
    27. New aspects of the structure of human hair on the basis of optical microscopic observations of disassembled hair parts. PubMed · 2015 · 1 citations
    28. Ultrastructural Characteristics of Neonate Scalp Hair Indian journal of science and technology · 2016
    29. 2P546 Structural Analysis of Curly and Straight Human Hair Fibers by Scanning Microbeam SAXS(52. Bio-imaging,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) Seibutsu Butsuri · 2006
    30. A function for Rac1 in the terminal differentiation and pigmentation of hair Journal of cell science · 2012 · 11 citations