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GlossaryCortex (Cerebral Cortex)

middle layer of hair responsible for strength and color

The cortex is the middle layer of a hair strand, located between the outer cuticle and the inner medulla. It is composed of long keratin filaments and is responsible for the hair's strength, color, and elasticity. The cortex contains melanin, which gives hair its color, and its structure can be altered by chemical treatments like coloring or perming.

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research Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain

33 citations, December 2015 in “Neuroendocrinology”

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals

11 citations, November 2021 in “International journal of molecular sciences”

Gut microbes significantly affect brain steroid levels.

research Sex Differences in Animal Models of Sodium Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence

9 citations, January 2022 in “Biology”

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

research Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

25 citations, April 2012 in “Acta Biomaterialia”

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

research Differential Expression of Retinoic Acid-Synthesizing (RALDH) Enzymes During Fetal Development and Organ Differentiation in the Mouse

232 citations, January 2002 in “Mechanisms of development”

Different enzymes are active in different parts of developing mouse organs.

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community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Bryan Johnson just dropped his anti hair loss formula

in Treatment 336 upvotes 8 months ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community Is it worth getting on oral minoxidil?

in Minoxidil 1 year ago

Evaluating the effectiveness of taking oral minoxidil as a hair loss treatment, in comparison to finasteride and topical minoxidil; discussing potential side effects of using oral minoxidil.

community Actor Paul Mescal, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. He just got nominated for an Oscar.

in Chat 353 upvotes 1 year ago

Actor Paul Mescal, who has a receding hairline, and how it affects his success in the entertainment industry. People discussed how styling can help disguise hair loss, and that hair loss doesn't necessarily mean one's appearance is immediately ruined. Treatments such as Minoxidil and Finasteride were mentioned to combat hair loss.

community Why I deleted my YouTube channel Part I

in Update 118 upvotes 3 years ago

A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

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