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research Experimental models to investigate the efficacy and bioequivalence of low dose topical corticoids
This study found that the vehicle of hydrocortisone impacts its absorption and therapeutic effectiveness, as demonstrated by efficacy tests using UV-erythema and vasoconstriction models.
research Concomitant androgenetic alopecia and alopecia areata successfully treated with a combination of topical corticosteroids and minoxidil solution: A case report
This report presents the first documented case of a 23-year-old male with both androgenetic alopecia and alopecia areata, showing clinical improvement with topical treatment and counseling.
research THE INFLUENCE OF ALLOXAN DIABETES, METHYLTHIOURACIL, CORTISONE AND ADRENALINE ON THE UTILIZATION OF GLUCOSE 14C AND L-CYSTINE 35S AND MITOTIC ACTIVITY BY HAIR FOLLICLES IN WHITE MICE
Alloxan diabetes, methylthiouracil, cortisone, and adrenaline affect how white mice hair follicles use glucose and cystine and their cell division.
research Effects of Age, Sex, and Coat Color on Hair Cortisol and DHEA as Stress Indicators in Sheltered and Adopted Cats
This study examined sheltered and adopted domestic cats, finding that dark coat color and living environment significantly influence hair cortisol and DHEA levels as stress indicators, while age and sex do not; adoption was associated with reduced long-term stress, underscoring its benefits for feline welfare.
research Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties
This study found that UV radiation exposure during a simulated Brazilian summer caused more significant mechanical damage to natural hair than bleaching, although both caused comparable structural alterations, with double bleaching leading to the most severe protein degradation.
research Psychological Assessments and the Stressfulness of Medically Indicated Abortion as Reflected by Hair Concentrations of Stress Hormones Cortisol and Testosterone: A Pilot Study
research Impact of acid (”progressive brush”) and alkaline straightening on the hair fiber: Differential effects on the cuticle and cortex properties
This study found that glyoxylic acid caused more protein loss in hair compared to traditional alkaline straighteners, though both types of treatments showed comparable effects on hair tensile strength.
research Neuroimmunology of Stress: Skin Takes Center Stage
This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
research Complications of Cushing's syndrome: state of the art
This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
research Neuroimmunoendocrine circuitry of the ‘brain-skin connection’
This study indicates that stress in mice recruits specific neuroimmunoendocrine elements, leading to neurogenic skin inflammation that inhibits hair growth and highlights the skin's role in stress response research.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
This review discusses the shift in toxicity profiles of cancer therapies from traditional chemotherapy to targeted agents, noting similar overall toxicities but with different side effects, and reports no new findings.
research Primary cicatricial alopecias: clinicopathology of 112 cases
This study reviewed the epidemiology and treatment of inflammatory cicatricial alopecias and highlighted the importance of scalp biopsies for accurate diagnosis in a mixed ethnic population at a university hair clinic.
research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABAAReceptors
This study demonstrated that stress-derived neurosteroid THDOC shifts from inhibiting to activating the HPA axis under stress, presenting potential therapeutic targets for stress-related disorders.
research The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults
This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.
research Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones
This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.
research Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management.
This review discusses recent advancements in congenital adrenal hyperplasia research, including improved diagnostic techniques, alternative treatments, and insights from long-term outcome data, but it reports no new clinical results.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products
This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.
research Treatment of Hirsutism With Spironolactone
This study reported that spironolactone at 200 mg/day significantly improved facial hair growth in women with hirsutism and showed a sustained reduction in ovarian androgens over one year.
research Alopecia areata
This article reviews current and emerging treatments for alopecia areata, including Janus kinase inhibitors, highlighting variability in clinical outcomes and the lack of sustained remission.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
These guidelines recommend testing thyroid function in patients with obesity due to common hypothyroidism, and highlight that weight loss is crucial for addressing hormonal imbalances, with only modest weight loss benefits from treating endocrine disorders.
research Lichen planus
This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
research Superficial granulomatous pyoderma: A localized vegetative form of pyoderma gangrenosum
In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.
research Alopecia areata
This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
research An Update of Congenital Adrenal Hyperplasia
This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
research Trilostane treatment of 78 dogs with pituitary‐dependent hyperadrenocorticism
This study found that trilostane was effective in resolving symptoms such as polyuria and polydipsia in many dogs with pituitary-dependent hyperadrenocorticism, with significant hormone level reductions observed.
research Hormone therapy for transgender patients
This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
research The human skin as a hormone target and an endocrine gland
This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
research Lupus erythematosus: systemic and cutaneous manifestations
This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.