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This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.

This study suggests that cortisol measured in human hair can effectively reflect increased production for up to six months, but its retrospective accuracy may be limited due to rapid decline in levels.

This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.

This review concluded that corticosteroids improve muscle strength and function in boys with Duchenne muscular dystrophy over short-term periods, but evidence on prolonging walking ability remains insufficient, and side effects are common.

This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.

In vitro, this study suggests that CRH may act as an autocrine hormone in human sebocytes, influencing lipid synthesis and potentially impacting skin disorders related to alterations in sebaceous lipid formation.

Hair cortisol analysis can help diagnose stress-related conditions but needs more refinement for widespread use.

This study found that hair cortisol levels were significantly higher in patients with Cushing's Syndrome compared to healthy controls, suggesting hair analysis can provide historical information on cortisol exposure.

In this study, researchers found a significant positive association between cortisol levels in hair and feces of domestic cats and dogs, suggesting hair cortisol assays could be a viable option for monitoring chronic stress.

This study developed and validated a method for extracting cortisol from human and animal hair, suggesting its potential as a biomarker for assessing chronic stress exposure.

This study observed that hair cortisol and cortisone concentrations were higher in older individuals and those with diabetes mellitus, highlighting their potential significance for assessing somatic health.

This review discusses the role of corticotropin-releasing hormone in human skin, focusing on its regulation, receptors, and functions, and highlights parallels with the hypothalamo-pituitary-adrenal axis; it reports no new research findings.

This study observed that cortisol concentrations in hair, indicating prolonged stress, are correlated between mothers and young children, suggesting potential heritable traits or maternal influence.

In this study, washing rhesus monkey hair with water or shampoo significantly reduced cortisol levels, suggesting potential underestimation of chronic stress hormone deposition in hair due to washing.

This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.

This study found that monthly oral prednisolone pulses of 300 mg were effective and safe for treating widespread alopecia areata, with 58.3% of patients achieving cosmetically acceptable hair growth.

This study validated a method for measuring cortisol levels in hair, which may serve as a biomarker for chronic stress in both humans and various animals.

In this study, researchers found that the prevalent Glu 410 Lys mutation in hHb6 and a new Glu 403 Lys mutation in hHb1 are linked to monilethrix, suggesting a mutational hotspot in type II hair keratins.

This study found that serum DHEA levels increase earlier and are higher in girls compared to boys through various stages of puberty, reflecting their earlier pubertal development.

This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.

This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.

This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.

This study confirmed that the diffusion of cortisol from blood is a biologically endogenous source of hair cortisol, correlating significantly with salivary cortisol levels in healthy humans.

In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.

In this study, ultraviolet irradiation and immersion in shampoo and hot water significantly reduced hair cortisol, illustrating a two-stage process of cortisol loss that may impact chronic stress assessment.

This study found that belimumab helped achieve low disease activity in over 40% of systemic lupus erythematosus patients in real-life settings, alongside reduced corticosteroid use and fewer flares.

This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.

This article discusses the relationship between cortisol, stress, and hair follicle function and highlights oral supplementation with a specific proteoglycan as a promising treatment for stress-related hair growth disorders, but it does not present new clinical results.

This study found that hair cortisol concentrations in sheep were significantly increased by extensive brushing or dexamethasone treatment, suggesting that external factors may affect its reliability as a chronic stress measure.

This study found that both Th1 and Th2 immune responses, along with IL-23 and IL-32 cytokine pathways, are active in alopecia areata lesions, and corticosteroid injections significantly altered these immune markers.