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    Glossary Connective Tissue Growth Factor

    protein involved in cell growth and tissue repair

    Connective Tissue Growth Factor (CTGF), also known as CCN2, is a protein that plays a crucial role in cell growth, differentiation, and tissue repair. It is particularly important in the formation of connective tissues, such as skin, tendons, and cartilage, and is involved in wound healing and fibrosis. Elevated levels of CTGF are often associated with fibrotic diseases, where excessive tissue formation can lead to organ dysfunction.

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    1. Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles Experimental dermatology · 2011 · 14 citations
    2. lncRNA H19 acts as a ceRNA to regulate the expression of CTGF by targeting miR-19b in polycystic ovary syndrome Brazilian Journal of Medical and Biological Research · 2020 · 21 citations
    3. Establishment of SV40T-transformed human dermal papilla cells and identification of dihydrotestosterone-regulated genes by cDNA microarray Journal of Dermatological Science · 2007 · 13 citations
    4. Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study Skin pharmacology and physiology · 2019 · 6 citations
    5. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    6. Desmodesmus pannonicus Water Extract Inhibits Melanin Synthesis and Promotes Wound Healing Life · 2024 · 1 citations
    7. The medicinal activity of lyophilized aqueous seed extract of Lepidium sativum L. in an androgenic alopecia model Scientific Reports · 2023
    8. Protective effects of taurine on human hair follicle grown <i>in vitro</i><sup>1</sup> International Journal of Cosmetic Science · 2006 · 26 citations
    9. Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond Experimental Dermatology · 2005 · 1 citations
    10. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    11. Growth of the Hair Physiological Reviews · 1954 · 521 citations
    12. Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies Experimental Dermatology · 2017 · 30 citations
    13. On the Horizon From the ORS Journal of the American Academy of Orthopaedic Surgeons · 2010 · 11 citations
    14. Effect of Microneedling Associated With Drug Delivery on Facial Rejuvenation: Clinical and Histological Evaluation International Journal Of Medical Science And Clinical Invention · 2021 · 1 citations
    15. Stem Cell: Current and Future State Springer eBooks · 2017
    16. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    17. Pathogenesis of androgenetic alopecia 2022
    18. Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior Cold Spring Harbor Perspectives in Medicine · 2014 · 42 citations
    19. Neuroimmunoendocrine circuitry of the ‘brain-skin connection’ Trends in Immunology · 2005 · 293 citations
    20. Sheep vibrissa dermal papillae induce hair follicle formation in heterotypic skin equivalents British Journal of Dermatology · 1994 · 21 citations
    21. Different levels of EGF, VEGF, IL‐6, MCP‐1, MCP‐3, IP‐10, Eotaxin and MIP‐1α in the adipose‐derived stem cell secretome in androgenetic alopecia Experimental Dermatology · 2022 · 1 citations
    22. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009 · 53 citations
    23. Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration The International Journal of Developmental Biology · 2021 · 12 citations
    24. Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor Journal of Veterinary Medical Science · 2016 · 8 citations
    25. Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways Journal of Molecular Medicine · 2007 · 66 citations
    26. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    27. Intraovarian vascular enhancement via stromal injection of platelet-derived growth factors: Exploring subsequent oocyte chromosomal status and in vitro fertilization outcomes 2020 · 25 citations
    28. Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing PLOS ONE · 2014 · 32 citations
    29. Hair Growth Promoting Effect of Dermal Papilla Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells in Athymic Nude Mice 2016
    30. The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study Dermatologic Surgery · 2017 · 70 citations