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Glossary Subcision

Subcision is a minimally invasive surgical procedure used to treat various skin conditions, including hair loss, by breaking up fibrous tissue that may be contributing to scarring or tethering of the skin. In the context of hair loss, subcision can help improve blood flow and promote the release of growth factors in the scalp, potentially enhancing hair follicle health and stimulating hair regrowth. Key distinguishing characteristics of subcision include its focus on the underlying connective tissue rather than the surface skin, and its ability to create a more favorable environment for hair follicles to thrive.

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Research

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research Long-lasting treatment for moderate-severe depressed facial scars: skin and hair derived new autologous tissue filler with subcision

8 citations , April 2020 in “Journal of dermatological treatment”

This study found that an autologous keratin and fibroblast tissue filler was effective for correcting moderate-severe depressed scars, with the majority of patients experiencing excellent improvement and no severe complications.

research Subcision: A Further Modification, an Ever Continuing Process

8 citations , January 2012 in “Dermatology Research and Practice”

This article describes a new subcision technique intended to simplify the procedure for surgeons without reporting clinical results or outcomes.

research Optimizing Post‐Acne Scar Treatment: A Pilot Comparative Study of Endo‐Radiofrequency Subcision With and Without Platelet‐Rich Plasma

3 citations , July 2025 in “Journal of Cosmetic Dermatology”

In this study, both Endo-RF subcision and the combination of Endo-RF subcision with PRP were shown to be safe and effective for improving post-acne scars, with the combination therapy potentially offering more desirable outcomes.

research Subcision with Blunt Cannula in Combination with Injection of PRP and Microneedling in Treatment of Acne Scar

1 citations , January 2023 in “The Egyptian Journal of Hospital Medicine”

This study found that combining platelet-rich plasma with microneedling and subcision was effective in treating atrophic acne scars in over 80% of patients with minimal adverse effects.

research 54481 A Comparative Analysis of CO2 Laser Therapy, RF Microneedling, TCA Cross, and Subcision on Post-Acne Boxcar Scarring in Skin of Color

September 2024 in “Journal of the American Academy of Dermatology”

Subcision is the most efficient, cost-effective, and safest treatment for post-acne boxcar scarring in skin of color.

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community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

46 upvotes 1 month ago

Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

community Following the recent IPO and the positive Phase 3 clinical data for VDPHL01 (extended-release oral minoxidil), what is the projected timeline for the FDA submission and the subsequent commercial availability on the market?

in Chat 4 upvotes 4 months ago

Veradermics' extended-release oral minoxidil is expected to be commercially available in 2027-2028, while another company, Minx, may release a similar product sooner. VDPHL01 is considered more clinically validated compared to Minx.

community Breezula 6 Month Topline Phase III Results Released

172 upvotes 9 months ago

Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

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