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Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Penile strangulation from hair can cause severe harm but can be treated if caught early.

Mouse genital development depends on male or female hormones for specific features.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.

Using a laser to remove hair in the urethra after hypospadias repair is effective and minimally invasive.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.

Some skin diseases and their treatments can negatively affect male fertility.

An elderly man with dementia suffered limb damage from rubber bands around his leg, highlighting the need for careful monitoring to prevent such injuries.

The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

A hair tightly wrapped around a toddler's toe caused severe crying and was treated by surgery.

A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

The patient has a rare skin condition that shows features of two known disorders.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.

PCOS increases sexual pain distress in infertile women.