58 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the heterogeneity of fibroblast subtypes in wound healing and reports no new results; the authors emphasize the potential for diverse fibroblast functions to lead to innovative therapies.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
53 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” This abstract omits specific findings and does not provide new research results.
32 citations
,
December 2014 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of polarity proteins in epidermal morphogenesis and homeostasis and discusses how their alteration may contribute to skin disease, but reports no new experimental findings.
31 citations
,
December 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the concept of epithelial-mesenchymal plasticity in wound healing and highlights restricting EMT for effective reepithelialization, but reports no new clinical results.
31 citations
,
November 2022 in “Cold Spring Harbor Perspectives in Biology” This review explores how epithelial cells from various niches in the skin respond and adapt during acute wound repair, highlighting the role of cellular plasticity in reepithelialization and restoring the skin's barrier function.
24 citations
,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
22 citations
,
October 2021 in “Cold Spring Harbor Perspectives in Biology” This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.
18 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the immune system's role in skin repair and regeneration, highlighting how biomaterials could potentially enhance fully functional skin regeneration through immunomodulatory mechanisms, but reports no new results.
16 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” This article explores how adult mammals can regenerate hair follicles after wounding and suggests that manipulating cell signals during healing might enhance this process, but provides no new experimental results.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.
8 citations
,
October 2022 in “Cold Spring Harbor perspectives in biology” The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
6 citations
,
December 2022 in “Cold Spring Harbor Perspectives in Biology” This review examines diverse regenerative strategies in animals and highlights how biochemical, immunological, and mechanical signals can work together for successful skin regeneration in adult mammals, but it reports no new experimental results.
4 citations
,
June 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the heterogeneity of dermal fibroblasts in healthy mouse and human skin and reports no clinical results; the authors highlight potential insights into physiological and pathological wound healing.
114 citations
,
January 2021 in “medRxiv (Cold Spring Harbor Laboratory)” This meta-analysis estimated that around 80% of patients who had COVID-19 experienced at least one long-term symptom, with fatigue being the most common reported effect.
32 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This systematic review found that long COVID symptoms, particularly fatigue, sleep disorder, and dyspnoea, were similarly prevalent in ongoing symptomatic COVID-19 and post-COVID-19 syndrome, but psychological issues and poor quality of life were more common in the latter.
21 citations
,
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.
20 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified six approved drugs that inhibited spike-mediated cell entry, potentially offering effective treatments against the initial stage of SARS-CoV-2 infection.
18 citations
,
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study suggests that two approved drugs may inhibit the SARS-CoV-2 helicase based on significant activity in laboratory models, offering hope for potential COVID-19 treatments.
13 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified four drugs, including brequinar and abiraterone acetate, that inhibited SARS-CoV-2 infection in vitro, providing potential candidates for repurposing to treat COVID-19.
11 citations
,
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that early treatment with azithromycin and either nitazoxanide, ivermectin, or hydroxychloroquine in COVID-19 patients may reduce viral shedding, symptom duration, and respiratory complications compared to untreated patients.
10 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that although Hispanic individuals in Northern Nevada faced socioeconomic disadvantages, their mortality rate from COVID-19 was lower than their non-Hispanic counterparts, who had more comorbidities.
10 citations
,
November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.
10 citations
,
May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that differences in the expression of genes related to lipid metabolism may play a major role in determining wool fiber diameter in sheep.
9 citations
,
October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that microglia play a crucial role in neurogenesis and brain regeneration in zebrafish by regulating inflammatory signaling, and their absence impairs these processes.
9 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies novel subpopulations of human epidermal melanocytes and specific transcriptional programs that differ from model organisms, providing insights into melanoma dedifferentiation.
8 citations
,
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that healthcare workers with a positive SARS-CoV-2 nasopharyngeal swab were most likely to report long-COVID symptoms, while seropositive workers without a positive swab had milder symptoms.
8 citations
,
September 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that women, younger individuals, and those with a low body mass index were more likely to develop long COVID symptoms, and even mild COVID-19 cases often experienced long-term residual symptoms.