5 citations
,
October 2020 in “Experimental dermatology” This study reports that during late embryogenesis and early postnatal development, K79-expressing keratinocytes change and die independently of sebaceous glands to form the hair follicle opening, potentially influencing conditions like ingrown hairs or acne.
2 citations
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July 2013 in “Veterinary dermatology” This study found that hair follicles from dogs with recurrent flank alopecia regenerated and regrew hair when grafted onto mice, suggesting systemic rather than local factors may drive the condition.
1 citations
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April 2017 in “Journal of Investigative Dermatology” In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.
January 2026 in “Buletin Veteriner Udayana” This study documented a case of Dipylidium caninum infection in a 4-month-old female dog, effectively treated with a deworming medication, resulting in significant improvement and no worms detected after five days. Routine deworming and maintaining hygienic conditions are recommended to prevent reinfection and transmission.
January 2025 in “Seven Editora eBooks” In this study, the authors reported a case of alopecia X in a German Spitz dog and found that treatment with orchiectomy and melatonin resulted in partial hair regrowth and improved the dog's dermatological condition.
January 2025 in “Epsilon Archive for Student Projects (University of Southampton)” In this study investigating goat herds in Zambia, both mange and orf were detected, but with low occurrence linked to diagnostic challenges and mild clinical signs; further research, especially in conditions favoring mange mites, is recommended to better understand and manage these diseases.
This review highlights the therapeutic potential of Hibiscus rosa-sinensis, detailing its significant medicinal value for treating various conditions such as wounds, infections, and diabetes, attributed primarily to its bioactive compounds like flavonoids and tannins.
November 2024 in “Journal of Translational Internal Medicine” This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.
January 2021 in “Acta Scientiae Veterinariae” In this study, researchers observed that administering the minimum dose of levothyroxine to a hypothyroid Dalmatian effectively restored normal skin condition and hormonal levels, suggesting levothyroxine's potential effectiveness in managing skin changes caused by hypothyroidism in dogs.
June 2026 in “Studia Biologica” This study found that in semi-coarse wool sheep of the Ukrainian Carpathian Mountain breed, changes in microflora and grease composition are linked to increased felting in wool, due to wetter, more alkaline fleece conditions that promote bacterial and mold growth and alter fatty acid balances.
November 2023 in “International Journal of Medical Case Reports and Reviews” This review discusses the potential and current applications of platelet-rich plasma in otolaryngology and reports no new clinical results; the authors note varying evidence for its effectiveness across medical conditions.
March 2026 in “Buletin Veteriner Udayana” In this case report, a combination therapy including pyrantel pamoate, chlorpheniramine maleate, vitamin B-complex, and topical candlenut oil effectively treated dermatitis and Ancylostoma spp. infection in a dog, leading to improvement in skin condition and hair growth after 14 days.
1 citations
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October 2022 in “JCI insight” In this study, conditional deletion of BRD4 in OX40-expressing cells of mice led to alopecia, dermatitis, and loss of hair follicle stem cell function, revealing BRD4's role in skin inflammation and stem cell regulation.
1 citations
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November 2022 in “Journal of Dermatological Treatment” This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.
1 citations
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May 2022 in “International Journal of Trichology” This article discusses hair loss conditions and available camouflage options after medical and surgical interventions fail, but it reports no new clinical findings.
January 2022 in “International journal of zoology and animal biology” This review discusses canine dermatomyositis, highlighting its genetic basis, clinical manifestations, and the need for improved treatment options, without reporting new findings.
10 citations
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November 2017 in “Journal of Investigative Dermatology” In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.
2 citations
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January 2025 in “Veterinary Dermatology” This study found that Pomeranian dogs with a woolly coat type and male dogs had a higher risk of developing Alopecia X in the Netherlands and Belgian regions studied.
In this study, researchers explored the diverse causes of alopecia in dogs, highlighting how factors such as infection, hormonal imbalances, and genetic conditions contribute to hair loss, and emphasized the importance of tailored diagnostics and treatment strategies.
January 2026 in “Animals” This study researched the dun coat color in Mongolian horses, finding that variations in TBX3 expression in different skin areas are linked to Bider markings, suggesting TBX3's role in this specific pigment pattern, while further investigation is needed on its regulation.
578 citations
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
73 citations
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December 2015 in “Nature Genetics” This study found that the Dun camouflage color in horses is due to TBX3 expression, which causes uneven pigment deposition, whereas non-dun coat colors result from regulatory mutations affecting TBX3 expression.
18 citations
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August 2024 in “eLife” This study investigated immune dysregulation in individuals with Down syndrome and found that treatment with the JAK inhibitor tofacitinib improved skin conditions like alopecia areata and reduced autoimmune markers without severe side effects. Additional research is necessary to understand its broader impacts.
17 citations
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September 2018 in “Matrix Biology” The researchers reported that mouse keratinocyte-specific deletion of laminin γ1 led to delayed coat pigmentation due to impaired melanocyte migration and differentiation, linked to altered laminin composition in the basement membrane.
3 citations
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November 2022 in “Experimental dermatology” This article discusses melatonin's role in mammalian coat color and its potential in melanoma treatment when used with chemotherapy, but reports no new clinical results.
2 citations
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March 1997 in “Veterinary Dermatology” This case report describes multiple skin tumors in an 11-year-old Doberman Pinscher with color dilution alopecia, but it remains unclear if the condition increases risk for such tumors.
October 2023 in “Cognizance journal” This study explores using agent-based modeling and nutrition science to predict and treat oral and dental diseases as alternatives to traditional incarceration for managing criminal behavior, but results are not reported.
8 citations
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February 2005 in “Veterinary dermatology” This study suggests that hair loss in Chesapeake Bay retrievers is a breed-specific syndrome characterized by unique histological features and abnormal steroid production, possibly influenced by familial factors.
90 citations
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July 2014 in “Conservation Physiology” This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.
31 citations
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November 2015 in “PloS one” In this study, modulating Tyrosinase expression altered mouse coat color by affecting melanosome accumulation, indicating that melanosome maturity plays a role in determining skin and hair color beyond total melanin content.