15 citations
,
November 2002 in “Cardiology in Review” This review discusses various adverse skin reactions linked to cardiovascular medications and reports no new clinical results, highlighting the need for vigilance when prescribing these drugs.
3 citations
,
July 2015 in “Australasian Journal of Dermatology” This letter discusses a case of iododerma in pregnancy linked to iodinated multivitamin use, but reports no new clinical findings.
3 citations
,
April 1989 in “Drug Information Journal” Side effects of drugs can lead to the discovery of new treatments.
1 citations
,
October 1974 in “Postgraduate medicine” New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” This article discusses the use of direct vasodilators and sympatholytic agents in hypertension management, highlighting their utility in specific cases like refractory hypertension and heart failure, but reports no new clinical results.
108 citations
,
October 2004 in “Anesthesiology” This review discusses surgical factors that may increase the risk of developing complex regional pain syndrome and describes potential preventive techniques but presents no new clinical results.
This review discusses the off-label use of drugs like Minoxidil, Aripripazole, and others, providing insights for physicians and pharmacists but reports no new clinical findings.
September 2018 in “Fertility and Sterility” This study found that in women with PCOS, lipid-induced NFκB activation is independent of obesity and exhibited evidence of LPS tolerance in combination with obesity and hyperandrogenism.
43 citations
,
May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
January 2024 in “RSC pharmaceutics” This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
July 1994 in “Annals of Pharmacotherapy” Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
5 citations
,
October 2021 in “Scientific Reports” This study suggests that certain climate factors, particularly UV index and precipitation, may influence seasonal flare patterns in children with alopecia areata, especially those with atopic conditions.
102 citations
,
September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
35 citations
,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
21 citations
,
May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
21 citations
,
October 1978 in “The Journal of Clinical Pharmacology”
10 citations
,
January 2014 in “Chemical and Pharmaceutical Bulletin” This study found that hair follicle-plugging reduced skin permeation of certain model drugs, with effects varying based on EtOH pretreatment and the drug being evaluated.
6 citations
,
January 2016 in “Springer eBooks” Invasomes effectively deliver drugs through the skin and have potential for improved treatments.
6 citations
,
July 2015 in “Australasian Journal of Dermatology” A man developed an allergic skin reaction after using brimonidine for rosacea.
February 2012 in “Journal of The American Academy of Dermatology”
2 citations
,
May 2021 in “Clinical Pharmacology in Drug Development” This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
393 citations
,
November 2000 in “Archives of General Psychiatry” This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.
254 citations
,
September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
228 citations
,
February 2003 in “Urology” This article discusses the side effects of androgen deprivation therapy for nonmetastatic prostate cancer, highlighting the need for clinical trials to systematically study these effects.
220 citations
,
August 1988 in “Clinical endocrinology” This review provides a comprehensive overview of melatonin's physiological roles, effects, and clinical implications, but it does not present new experimental findings.
202 citations
,
June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
183 citations
,
January 1987 in “British Journal of Anaesthesia” This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.
172 citations
,
December 2004 in “Journal of The American Academy of Dermatology” In this study, demodicoses were found to be relatively common among immunocompetent patients, with a notable overlap with papulopustular rosacea.