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Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Most people with basal cell carcinoma on their head or neck were 60-70 years old, and it often came back even after being fully removed, especially in certain areas and types.

Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.

Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Healthcare providers need better education and policies to serve transgender individuals effectively.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

Immigrant Latino workers in North Carolina, especially in poultry processing, often have skin diseases like fungal infections and acne.