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The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.

Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

A 12-year-old girl in Saudi Arabia with Focal dermal hypoplasia showed skin and dental symptoms, highlighting the condition's variability and the need for personalized treatment.

Dr. Rodney Sinclair uses a detailed grading system to diagnose female pattern hair loss, recommends daily spironolactone and minoxidil for treatment, and believes genetics play a role in the condition.

The study found that hair fragility in Pili annulati may be caused by cavities and damage within the hair shafts.

Stump-tailed macaque best for researching hair loss causes and treatments.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

Increased cell death and reduced cell growth in hair follicles contribute to baldness.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Hair microscopy is useful for diagnosing certain hair loss conditions but has limitations and must be interpreted carefully.

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.

Over half of the children had abnormal hair under a microscope, with many having genetic hair conditions.

Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.