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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Removing part of the vitamin D receptor stops vitamin D from working properly.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

CDP is crucial for lung and hair follicle cell development.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

K6hf is a unique protein found only in a specific layer of hair follicles.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.