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    Glossary Cancer Stem Cells

    small subset of tumor cells that can self-renew and differentiate

    Cancer Stem Cells (CSCs) are a small subset of cells within a tumor that possess the ability to self-renew and differentiate into various cell types found in the cancer. These cells are thought to be responsible for tumor growth, metastasis, and recurrence after treatment, making them a critical target for cancer therapies.

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    1. Normal stem cells and cancer stem cells: similar and different Seminars in Cancer Biology · 2010 · 126 citations
    2. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer Nature Reviews Genetics · 2018 · 124 citations
    3. Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies Journal of Cellular and Molecular Medicine · 2009 · 36 citations
    4. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    5. Skin in the Game: Stem Cells in Repair, Cancer, and Homeostasis Cell · 2020 · 2 citations
    6. Stem and cancer cells Wnt long telomeres Nature Cell Biology · 2012
    7. Skin stem cells and tumor growth : functions of collagen XVIII in hair follicle cycling and skin cancer, and Bmx tyrosine kinase in tumor angiogenesis 2014 · 3 citations
    8. Cell-intrinsic mechanisms governing stem cell quiescence and regulating cancer progression in mammalian skin CU Scholar (University of Colorado Boulder) · 2015
    9. Colon Cancer Stem Cells: Promise of Targeted Therapy Gastroenterology · 2010 · 411 citations
    10. Intestinal Stem Cell Imaging in Colorectal Cancer Screening Journal of Stem Cells and Regenerative Medicine · 2013 · 3 citations
    11. Stem Cells in Nonmelanoma Skin Cancer 2004
    12. Inflammatory auxo-action in the stem cell division theory of cancer PeerJ · 2023 · 2 citations
    13. Role of  -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer Cold Spring Harbor Symposia on Quantitative Biology · 2008 · 61 citations
    14. Context-dependent effect of sPLA2-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer EBioMedicine · 2019 · 13 citations
    15. The dual role of stem cell-specific Bcl-2 function for epidermal regeneration and cancer 2019
    16. Shaping epithelial tissues by stem cell mechanics in development and cancer Nature Reviews Molecular Cell Biology · 2025 · 12 citations
    17. Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance Genes & Diseases · 2023 · 56 citations
    18. Stem cells in tissues, organoids, and cancers Cellular and Molecular Life Sciences · 2019 · 76 citations
    19. Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties Discover Oncology · 2026
    20. An Approach to Identify Targets of Breast Cancer Stem Cells MacSphere (McMaster University) · 2007
    21. Stem cell activity shapes the pleiotropic effects of IFN-γ and TGF-β in autoimmune diseases, infections, and cancer, and drives autoimmune flares and remissions Frontiers in Immunology · 2025
    22. Conditioned media from human pluripotent stem cell‐derived cardiomyocytes inhibit the growth and migration of lung cancer cells Journal of Cellular Biochemistry · 2023 · 1 citations
    23. Peer Review #3 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)" 2023
    24. Targeted delivery of siRNA to human cancer and human embryonic stem cells with cell level resolution Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) · 2016
    25. Peer Review #4 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)" 2023
    26. Peer Review #1 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)" 2023
    27. Peer Review #2 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)" 2023
    28. Peer Review #4 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.2)" 2023
    29. Peer Review #3 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.2)" 2023
    30. Peer Review #1 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.2)" 2023