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Deregulation of stem cell function is central to the development of some cancers.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

Targeting colon cancer stem cells might lead to better treatment results.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.