February 2026 in “Journal of Aesthetic Medicine” This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.
November 2025 in “Journal of Natural Fibers” This study reviews the potential to repurpose human hair waste, often discarded from places like barber shops and hospitals, into valuable raw materials for chemical and materials science applications, despite existing challenges in its utilization.
August 2025 in “Plastic and Aesthetic Research” This review discusses recent advancements in microneedle technology for hair loss treatment, highlighting their ability to enhance drug delivery and improve hair follicle survival in transplantation, while also exploring their potential integration with tissue engineering to address regeneration challenges.
May 2024 in “International Journal of Nanomedicine” This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.
This review summarizes the current applications and mechanisms of self-assembled peptide hydrogels in promoting skin, bone, and nerve regeneration, highlighting their potential due to their biocompatibility and supportive role in tissue healing.
46 citations
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January 2020 in “Research” This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.
45 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses various in vitro and in vivo models for studying hair follicle function, noting their potential in developing new treatments for hair disorders but reports no new results.
44 citations
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June 2023 in “Cell Reports” This study investigated dermal fibroblasts in mouse skin using single-cell RNA sequencing and identified signaling pathways that influence adipogenesis, finding that IL-1-NF-κB promotes, while WNT-β-catenin inhibits, the adipogenic potential of these cells, with implications for wound healing and scar formation.
5 citations
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February 2025 in “Scientia Horticulturae” This study found that tomato plants inoculated with Enterobacter sp. SA187 grew better under salinity and heat stress, showing improved biomass, ion balance, chlorophyll content, and antioxidant enzyme activity, potentially enhancing crop tolerance to environmental stress.
3 citations
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July 2025 in “Gels” This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.
February 2024 in “Journal of Education, Health and Sport” This review discusses the regenerative properties of exosomes and their potential clinical applications in regenerative medicine, highlighting their role in restoring health and vitality.
1 citations
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July 2022 in “Pakistan biomedical journal” This review discusses ethanol-based transethosome vesicles for drug delivery through the skin, but reports no new clinical results.
June 2026 in “JOURNAL of QASSIM UNIVERSITY FOR SCIENCE” This article discusses various management strategies for polycystic ovarian syndrome but reports no new clinical results, emphasizing the need for comprehensive treatment approaches involving lifestyle changes, pharmaceuticals, and potential genetic insights.
July 2025 in “Journal of Investigative Dermatology”
2 citations
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January 2026 in “Frontiers in Endocrinology” This review discusses the impaired functionality of regulatory T cells in the pancreas during the development of Type 1 diabetes, highlighting their role in disease pathogenesis, potential of Treg-based therapies, and challenges in clinical applications.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The abstract for Roota Hair Growth describes a product combining botanical extracts with clinically-tested ingredients to target hair thinning, breakage, and scalp fatigue by blocking DHT, strengthening hair fibers, and revitalizing the scalp through a precision roll-on applicator, offering a natural alternative for healthier hair.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The investigators highlighted Roota Hair Growth as a promising botanical solution for hair concerns, suggesting it may improve hair health by addressing the root causes of thinning, breakage, and scalp fatigue.
3 citations
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September 2025 in “Frontiers in Immunology” This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.
16 citations
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March 2022 in “Journal of Infection” This study observed that sera from Covaxin-vaccinated individuals showed reduced neutralization ability against the Omicron variant compared to B.1, Beta, and Delta variants, with breakthrough infections boosting immune response more effectively than vaccination alone.
April 2026 in “Future Medicinal Chemistry” This article discusses the impact of PROTACs technology in transforming drug discovery with its novel degradation mechanism, but it reports no new experimental findings.
August 2025 in “Aesthetic Plastic Surgery” This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.
January 2025 in “Universitätsbibliothek Stuttgart” This article reviews the current challenges, innovations, and prospects of cosmetics designed to prevent hair loss and encourage hair growth, highlighting evolving technologies like gene therapy and the need for multidisciplinary approaches.
September 2025 in “International Journal of Pharmacy and Biomedical Engineering” This review highlights the potential of drug repurposing to offer faster and more cost-effective solutions compared to traditional drug development methods by leveraging existing medications for new uses; however, regulatory and intellectual property challenges remain significant barriers.
July 2026 in “Bioactive Materials” This study demonstrated that degradable core-shell cryomicroneedles loaded with hair follicle organoids supported natural-like hair regeneration in mice, offering a promising approach for controllable follicular unit regeneration in baldness.
May 2026 in “Biotechnology and Bioengineering” This review discusses recent breakthroughs in 3D bioprinting for hair regeneration, highlighting developments like biomimetic dermal papilla spheroids and follicle organoids, but notes that clinical application is hindered by challenges in integrating vascular and nerve systems and managing hair-cycle dynamics.
22 citations
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May 2012 in “Dermatologic Therapy” This article reviews the lack of major breakthroughs and limited therapeutic options for extensive hair loss, emphasizing the need to address its psychological impact; it reports no new clinical results.
September 2015 in “International Society of Hair Restoration Surgery” This article discusses the role of hair follicle stem cells in potential breakthroughs for hair cloning and follicular cell implantation, but reports no new clinical findings.
This chapter discusses the benefits and limitations of FUE and FUT hair restoration techniques, the author's personal preferences in performing transplants, and potential breakthroughs in hair loss treatment, as compiled from recent literature.
December 2011 in “Asia-Pacific biotech news” This collection of research news highlights various scientific advancements, including discoveries in anti-cancer compounds, new cell types that boost immunity, and a potential Parkinson's breakthrough in Australia, among others from China, India, Korea, Singapore, and Thailand.
179 citations
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September 1998 in “BMJ” This article reviews the pathogenesis, genetic basis, and recent treatment breakthroughs for androgenetic alopecia but reports no new clinical findings.