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This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.

In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.

This study found that α-spinasterol treatment significantly reduced testosterone propionate-induced prostatic hyperplasia in rats, suggesting potential benefits for managing benign prostatic hyperplasia.

This study identified that downregulation of the gene BcFLA1 decreases root hair length in Brassica carinata under phosphate-deficient conditions, highlighting its role in root hair elongation.

This study reports that using ascorbic acid or orlistat can significantly inhibit the metabolism of testosterone esters into malodorous metabolites by axillary bacteria, suggesting potential new deodorant applications.

This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.

This study found that ethanol extracts of Allium tuberosum Rottler ex Spreng significantly promoted hair growth in mice, possibly by increasing IGF-1 expression.

This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against Onchocerciasis by targeting Onchocerca volvulus and its endosymbiont; further research is suggested to confirm their efficacy.

This article reviews the effectiveness of adrenal cortex compounds E and F in treating various connective tissue disorders and reports no new clinical findings.

This review provides an overview of clinically approved small molecule drugs targeting androgen receptors and discusses therapeutic applications, without presenting new experimental results.

This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.

This study found that hydroxycinnamate derivatives, especially a compound named 10a, effectively inhibited SRD5A1 activity and protein expression in cell assays, suggesting potential for treating androgen-related conditions.

This study found that neuroactive steroids like DHEA and pregnenolone influence cocaine-induced appetence in mice through their interaction with the ς₁ receptor, suggesting a role in individual vulnerability to addiction.

This review highlights that clascoterone, a newly FDA-approved topical androgen antagonist, effectively reduces both non-inflammatory and inflammatory acne lesions with no systemic effects, making it a promising new option for acne treatment in both male and female patients.

This review explores the mechanisms of intratesticular control of steroidogenesis and indicates the need for further controlled studies; it presents no new experimental findings.

This study found that cellular retinoic acid-binding proteins and fatty acid-binding proteins are dynamically expressed in skin development and respond differently to retinoic acid, β-catenin, and Notch signaling.

This study suggests that estrogen regulates vitamin A metabolism in skin tissues in a sex-dependent manner, which may have implications for treating acne, hair loss, and skin immunity.

In this study, the n-hexane fraction of wheat bran significantly promoted hair growth in rat vibrissa follicles and triggered the telogen-anagen transition in C57BL/6 mice, likely through cell cycle and Wnt/β-catenin signaling pathways.

This study found that several synthesized compounds were potent inhibitors of human steroid 5alpha-reductase type 2 and reduced prostate weights in treated rats, with compound 15 showing promise for potency in humans.

This study found that in vitro environments simulating testosterone levels in elderly males, testosterone and its metabolite DHT significantly reduced macrophages' ability to phagocytize MRSA and Pseudomonas aeruginosa, suggesting AR manipulation and inhibiting testosterone-DHT conversion might help fight wound infections in the elderly.

This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.

This review discusses treatment options for hereditary angioedema and reports no new results; it highlights concerns about androgen side effects and mentions approved alternatives with fewer serious adverse effects.

This review explores enzyme inhibitors from gorgonians and soft corals and highlights their potential industrial and biomedical applications, but it reports no new experimental results.

This study will explore whether combination therapy with either dutasteride or finasteride and an α1 blocker is more effective than monotherapy for treating BPH, but it reports no new results.

In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.

This study found that expressing certain PIN proteins in Arabidopsis root hairs inhibited growth by decreasing auxin levels, while PIN5 slightly stimulated growth, demonstrating differential effects on auxin transport.

This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.

This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.

This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.