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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Low selenium intake may delay puberty in boys but not in girls.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

Saw palmetto may cause erectile dysfunction and needs better safety monitoring.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

SOX9 is essential for the development of various organs and hair follicles.

Stem cell therapies show promise for treating hair loss, but more research is needed to understand their safety and effectiveness.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Both estrogens and androgens are important for health in both males and females.

Higher early lead exposure is linked to delayed puberty in girls.

People with Alopecia areata often have lower Vitamin D levels, which might affect the severity of their condition.

Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.

The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.

A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.

Middle-aged skin shows aging signs, and quercetin might help delay them.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

3D bioprinting is advancing in plastic and reconstructive surgery, especially for creating tissues and improving surgical planning, but faces challenges like vascularization and material development.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

The rash on the infant indicated a serious underlying condition.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Baricitinib reduces inflammation and improves cell health in premature aging cells.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.