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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Older adults in Ottawa commonly have skin conditions like sun damage, dry skin, and hair loss.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Skin aging reflects overall body aging and can indicate internal health conditions.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Gene mutations can cause problems in male genital development.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Royal jelly can protect the heart from damage caused by paclitaxel.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.