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Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Latanoprost can make eyelashes longer, thicker, and darker.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Minoxidil promotes hair growth but stops working when discontinued.

Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Mothers and newborns with dental fillings had higher mercury in their hair, but getting fillings during pregnancy didn't raise mercury levels further.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Fat cells are important for tissue repair and stem cell support in various body parts.

Mutations in the KRT85 gene cause hair and nail problems.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.