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This case report suggests that poor hair and nail growth in children with autism spectrum disorder and developmental delay may indicate a biotin-responsive condition, as biotin and acetazolamide therapy improved symptoms and school performance in the reported patient.

Biotin supplements did not significantly reduce hair loss in rats on valproic acid.

This article discusses treatments for male pattern alopecia, noting variable response rates, but reports no new clinical results.

This study found that adding inositol or biotin to a pig's diet without sulfathalidine had no effect on growth or feed efficiency, but both helped alleviate deficiency symptoms caused by sulfathalidine.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

This study found that a new hair loss lotion containing various cosmetic ingredients significantly increased total hair fibers and anagen hairs in individuals with androgenetic alopecia and telogen effluvium, while also improving visual hair characteristics and receiving positive user feedback without adverse effects.

This review discusses the role of biotin in enzyme function and its effects on hair, skin, and nail health, noting that significant improvements are mostly seen in people with biotin deficiency, and reports no new clinical results.

In this study, biotin supplementation was found to significantly increase wool follicle viability and metabolic activity in vitro, with the highest effects observed at 0.5 mg L⁻¹ concentration.

This study found that a majority of dermatologists in Saudi Arabia believe in using vitamins and minerals to treat hair loss but emphasized the need for more research to confirm their effectiveness.

This study found that a topical compounded formulation may improve hair density and general appearance in male patients with androgenetic alopecia after 6 months of use.

This review discusses supplements used to alleviate side effects of chemotherapy, highlighting various natural remedies, but reports no original clinical research findings.

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

This review explores the role of nutritional factors in hair loss, noting that iron and l-lysine supplementation may benefit some individuals, while excessive supplements can lead to hair shedding.

This study reports that permanent and severe alopecia is a newly identified complication of the FEC 100–docetaxel regimen used for adjuvant breast cancer treatment.

This study reported successful treatment of biotin deficiency in three patients receiving total parenteral nutrition, suggesting current biotin supplementation recommendations may be inadequate to maintain normal biotin status.

This study found that male germ-free rats fed semisynthetic diets do not grow as rapidly as their conventional counterparts and require dietary biotin for normal metabolism and folic acid biosynthesis.

This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.

This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.

In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.

This review discusses various therapeutic options for alopecia areata and reports no new clinical results; treatments may manage symptoms but do not cure the condition.

This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.

This study found that biotin deficiency in mice led to reduced zinc levels, disappearance of epidermal Langerhans cells, and increased ATP production, resulting in prolonged irritant contact dermatitis.

This study found that hemodialysis patients taking water-soluble vitamins had a 16% lower mortality risk compared to those not taking any, but the specific supplementation needed remains unclear.

This report concludes that no cause and effect relationship has been established between consuming KF2BL20 and maintaining normal hair in healthy adults.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

In this study, the derivation of certain topological indices was used to represent the molecular structure of drugs for alopecia treatment, like Minoxidil and Finasteride, which may support medication investigations, especially in resource-limited settings.

In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.

This review highlights the increasing use of herbal cosmetics for maintaining healthy hair growth and preventing premature greying, influenced by rising living standards and interest in personal care.

This study observed that hirsutism, alopecia, and acne are the most common androgenic symptoms in women with PCOS, with treatments including biotin, minoxidil, and over-the-counter acne medications.

Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.