research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
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research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Steroid 5α-Reductase Inhibition by Polymethoxyflavones
Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Discriminating in Favor of or Against Men with Increased Risk of Finasteride-Related Side Effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research Post-Finasteride Syndrome: A Review of Current Literature
Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.
research Introduction to Endocrinological Aspects of Andrology: What Is New?
The document discusses new insights into how hormones affect male sexual health and related conditions.
research Long-Term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial
Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
research Biofeedback Treatment for Dysfunctional Voiding Diagnosed in Adulthood
Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.
research Incidence of Serious Infectious Events with Methotrexate Treatment: Meta-Analysis of Randomized Controlled Trials
Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.
research Urinary Symptoms in Patients with Androgenetic Alopecia
Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Comparison of Finasteride (Proscar) and Serenoa Repens (Permixon) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers
Finasteride works better than Permixon in reducing dihydrotestosterone levels.
research Effects of 5-Alpha Reductase Inhibitors on Erectile Function, Sexual Desire, and Ejaculation
5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Maximum Efficacy of Finasteride Is Obtained Within 6 Months and Maintained Over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate links to more hair loss, but age of onset doesn't affect it.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Oral Ivermectin in the Treatment of Scabies
Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.
research Finasteride-Associated Cataract And Intraoperative Floppy-Iris Syndrome
Finasteride may cause cataracts and floppy-iris syndrome.
research The Placebo Effect And Randomized Trials: Analysis Of Conventional Medicine
The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
research Assessing Finasteride-Associated Sexual Dysfunction Using the FAERS Database
Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
research Economic Analysis of Finasteride: A Model-Based Approach Using Data from the Proscar Long-Term Efficacy and Safety Study
Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Facial Hidradenitis Suppurativa in a 28-Year-Old Male Responding to Finasteride
Finasteride helped treat a 28-year-old's facial skin condition.
research Effects of Long-Term Treatment With Finasteride (MK-906), a 5-Alpha Reductase Inhibitor, on Circulating LH, FSH, Prolactin, and Estradiol
Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Post-Finasteride Syndrome – Does It Really Exist?
Post-finasteride syndrome's existence is uncertain; more research needed.