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    Glossary Basement Membrane

    thin layer separating epithelial cells from underlying connective tissue

    The basement membrane is a thin, fibrous layer that lies between the epithelial cells (which line surfaces and cavities of organs) and the underlying connective tissue. It provides structural support, acts as a barrier to regulate the movement of cells and molecules, and plays a crucial role in tissue repair and regeneration. In the context of hair, the basement membrane surrounds hair follicles, helping to anchor them in place and maintain their structure.

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    1. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    2. Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles Experimental Dermatology · 2003 · 29 citations
    3. Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis? 2018 · 13 citations
    4. The Appearance of Four Basement Membrane Zone Antigens in Developing Human Fetal Skin Journal of Investigative Dermatology · 1984 · 65 citations
    5. Basement membrane changes in lichen planopilaris Journal of the European Academy of Dermatology and Venereology · 2009 · 7 citations
    6. A Novel Marker of Tissue Junctions, Collagen XXII Journal of Biological Chemistry · 2004 · 226 citations
    7. Epidermolysis bullosa in animals: a review Veterinary Dermatology · 2014 · 33 citations
    8. Alopecia in Epidermolysis Bullosa Dermatologic Clinics · 2009 · 21 citations
    9. Heterogeneous disease: A child case of lichen planus pemphigoides triggered by varicella The Journal of Dermatology · 2011 · 19 citations
    10. Severe diffuse non-scarring hair loss in systemic lupus erythematosus - clinical and histopathological analysis of four cases Journal of the European Academy of Dermatology and Venereology · 2011 · 15 citations
    11. Hair Loss in Autoimmune Cutaneous Bullous Disorders Dermatologic Clinics · 2011 · 12 citations
    12. P‐35 
Nonlethal junctional epidermolysis bullosa in a dog Veterinary Dermatology · 2004 · 2 citations
    13. A Monoclonal Antibody Established from the Immunization of Basal Cell Carcinoma (BCC) Tissues Reacts to the Intercellular Space of BCC and Hair Follicles Journal of dermatology · 2002 · 1 citations
    14. P029 A case of atypical bullous pemphigoid British Journal of Dermatology · 2026
    15. SUMMARIES OF PAPERS British Journal of Dermatology · 1973 · 1 citations
    16. The role of inflammation and immunity in the pathogenesis of androgenetic alopecia. PubMed · 2011 · 19 citations
    17. Reply to comment on: Pattern hair loss. Assessment of inflammation and fibrosis on histologic sections Journal of The American Academy of Dermatology · 2020 · 1 citations
    18. VINCENT BARRANCO, M.D., EDITOR 2121 EAST 21ST STREET, P.O. BOX 52588 TUESA, OK 74152-0588. International Journal of Dermatology · 1996
    19. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    20. Systemic lupus erythematosus in a filly. PubMed · 1990 · 23 citations
    21. Two Dogs with Juvenile-Onset Skin Diseases with Involvement of Extremities Journal of Veterinary Medical Science · 2010 · 4 citations
    22. Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle. PubMed · 1992 · 45 citations
    23. Expression of basement membrane components through morphological changes in the hair growth cycle Developmental Biology · 1985 · 53 citations
    24. Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication Matrix Biology · 2016 · 57 citations
    25. An <i>mTurq2-Col4a1</i> mouse model allows for live visualization of mammalian basement membrane development 2023
    26. An <i>eGFP-Col4a2</i> mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis The Journal of Cell Biology · 2024
    27. The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche Cell · 2011 · 294 citations
    28. Spatial and temporal control of laminin-511 and -332 expressions during catagen Journal of Dermatological Science · 2010 · 6 citations
    29. The Cytology and Cytochemistry of the Wool Follicle International review of cytology · 1979 · 90 citations
    30. The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair 2001 · 46 citations