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GlossaryLamina Densa

dense layer of the basement membrane providing structural support

The lamina densa is a dense layer of the basement membrane, which is a specialized structure that supports and separates different types of tissues in the body. It is primarily composed of collagen and other proteins, providing structural integrity and filtering functions, crucial for tissue health and function.

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research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction

13 citations, December 1983 in “Canadian journal of zoology”

Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.

research α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis

45 citations, May 2003 in “Journal of Cell Science”

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

13 citations, June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

research Regeneration of the Epidermis and Mucosal Epithelium on the Basement Membranes

2 citations, December 2003 in “Medical electron microscopy”

The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.

research The Function and Structure of the Skin

4 citations, November 2014

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

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