research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
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research Congenital Adrenal Hyperplasia: A Review of 21-Hydroxylase Deficiency and Diagnostic Challenges
The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.
research Is Increased Constitutive Skin and Hair Pigmentation an Early Sign of Puberty?
Darker skin in 10-year-old girls may be an early sign of puberty.
research A Novel NR5A1 Gene Mutation Causing 46, XY DSD Without Adrenal Insufficiency in an Immigrant Boy from Dominican Republic
A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.
research Identification of a Novel Homozygous LAMB3 Mutation in a Chinese Male With Junctional Epidermolysis Bullosa and Severe Urethra Stenosis: A Case Report
A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.
research A 14-Year-Old Female with Primary Amenorrhea
A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.
research Madarosis: A Marker of Many Maladies
Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
research Guidelines for Clinical Trials of Frontal Fibrosing Alopecia: Consensus Recommendations from the International FFA Cooperative Group
Experts agreed on guidelines to improve research on Frontal Fibrosing Alopecia.
research Lichen Planopilaris in Women: A Retrospective Review at Mayo Clinic (1992-2016)
Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.
research The Diagnosis of Androgenetic Alopecia in Children: Considerations of Pathophysiological Plausibility
AGA in children needs careful diagnosis due to low androgen levels and possible other causes.
research Alopecia Areata: Genetic and Immunological Insights
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Cosmetopoeia of African Plants in Hair Treatment and Care: Topical Nutrition and the Antidiabetic Connection
African plants can treat hair issues and may help with diabetes.
research Literature Reviews on Cosmetic and Reconstructive Surgery
Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.
research Antifungal Activity and Hair Growth Stimulation of Purple Sweet Potato Leaf Fraction (Ipomoea Batatas) and Its Molecular Mechanism Through Androgen Receptor Inhibition
Purple sweet potato leaf extracts can help treat hair loss and fungal infections.
research Pilose Antler Extract Promotes Hair Growth in Androgenic Alopecia Mice by Promoting the Initial Anagen Phase
Pilose antler extract helps hair grow in mice with a type of hair loss by speeding up the growth phase.
research Hair Diseases: Alopecia Areata and Androgenetic Alopecia
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.
research Nonclassic Congenital Adrenal Hyperplasia: Pathophysiology, Genetics, and Management
Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome
A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Biphenotypic Leukemia
Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.
research A Case of Scarring Alopecia
The woman was diagnosed with lichen planopilaris and can be treated with corticosteroids.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Thyroid Autoimmunity in Patients with Skin Disorders
People with alopecia areata often have thyroid autoimmunity.
research Computer-Based Screening of Selected Phytoconstituents from Cyperus Rotundus Linn. Against 5 Alpha Reductase Enzyme
Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.
research Scoping Review on the Use of Drugs Targeting JAK/STAT Pathway in Atopic Dermatitis, Vitiligo, and Alopecia Areata
Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
research Laser Treatment in Hirsutism: An Update
Laser treatment can effectively reduce unwanted hair growth, particularly for people with fair skin and dark hair.
research Desmoglein 4 Mutations Underlie Localized Autosomal Recessive Hypotrichosis in Humans, Mice, and Rats
Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.
research Dermatopathia Pigmentosa Reticularis: A Rare Reticulate Pigmentary Disorder
Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.