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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

Muscles can make their own androgens, which may help muscle growth.

The article concludes that understanding Frontal Fibrosing Alopecia (FFA) is crucial for effective treatment, which includes medication like 5α-reductase inhibitors and hydroxychloroquine.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Mice with human gene experienced hair loss when treated with DHT.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Testosterone helps human pancreatic cells increase insulin release.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Finasteride helps hair regrowth in frontal fibrosing alopecia.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

New treatments for Frontal Fibrosing Alopecia show promise, especially finasteride and dutasteride, with most patients seeing improvement or stabilization.

The letter is skeptical about the effectiveness of anti-androgen therapy for COVID-19 and calls for strong evidence from clinical trials.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.