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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Oxidative stress contributes to hair graying and loss as we age.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Hair loss in men treated best with early medication or transplant, new treatments researched.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.