research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
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research Polycystic Ovary Syndrome: A Common But Often Unrecognized Condition
Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.
research Sequential Estrogen-Progestin Addition to Gonadotropin-Releasing Hormone Agonist Suppression for the Chronic Treatment of Ovarian Hyperandrogenism: A Pilot Study
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
research Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Diseases of the Hair and Nails
Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.
research Hyperandrogenism in Adolescent Girls: Diagnosis and Management
Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.
research Frontal Fibrosing Alopecia: Clinical Features, Diagnosis, and Treatment Challenges
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Androgen Dependence of Hirsutism, Acne, and Alopecia in Women
Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
research Idiopathic Hirsutism: Androgen Role and Treatment Options
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research An Update on Diagnosis and Treatment of Female Pattern Hair Loss
Updated treatments for female hair loss include minoxidil, antiandrogens, hair transplants, and light therapy.
research Management of Hair Loss in Women
Certain medications and maintaining adequate iron levels can help manage women's hair loss.
research News on PCOS
Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.
research Hormone Treatment for the Adult Transgender Patient
Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
research Alpha-Hydroxy Acid-Based Cosmetic Procedures
Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
research Understanding and Addressing Hair Disorders in Transgender Individuals
Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.
research Androgenetic Alopecia: An Autosomal Dominant Disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research Antiandrogens for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials
Antiandrogens are somewhat effective in reducing excessive hair growth in women.
research Androgenetic Alopecia
AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.
research Hirsutism, Postpartum Telogen Effluvium, and Male Pattern Alopecia
Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea
The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
research The Use of Hormonal Antiandrogen Therapy in Female Patients with Acne: A 10-Year Retrospective Study
Hormonal antiandrogen therapy for acne is underused and can reduce the need for antibiotics.
research Clinical Updates in Hair
Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
research Recommendations for Endocrine Treatment of Patients with Gender Dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
research Side Effects of Androgen Deprivation Therapy: Monitoring and Minimizing Toxicity
Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.
research Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research The Hyperandrogenic-Insulin-Resistant Acanthosis Nigricans Syndrome: Therapeutic Response
Most patients improved with oral contraceptives, but some needed additional treatment.
research Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients
Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.