research Spironolactone in Dermatology: A Mini Review
Spironolactone may be effective for acne and other skin conditions and could be used more in treatment.
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research An Adult With Hair Loss: A Rare Case of Non-Classical 3β Hydroxysteroid Dehydrogenase Deficiency
A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.
research Comparison of Clinical and Biochemical Markers of Hirsutism in Polycystic Ovary Syndrome: A Study from a Teaching Hospital in Sri Ramachandra Institute, Chennai, India
Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
research A 14-Year-Old Female with Primary Amenorrhea
A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.
research Giant Bilateral Myelolipomas in a Patient with Congenital Adrenal Hyperplasia
A patient with untreated congenital adrenal hyperplasia had large benign tumors in her adrenal glands removed, improving her symptoms.
research Virilisation in a Young Woman: A Case Demonstrating the Importance of Co-Located Mental and Primary Healthcare
The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.
research Genome-Wide Shifts in Gene Expression Induced in Theca-Interstitial Cells by Inflammatory Stimuli
African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.
research Ovarian Hyperthecosis Coexisting with an Incidental Adrenal Lesion: Challenges in the Diagnostic Approach
Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.
research Investigating the Mechanisms Underlying Effects of Testosterone on Blood Pressure in Normotensive and Hypertensive Rats
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
research Aldosterone-Producing Adrenal Adenoma
Removing an adrenal gland tumor improved a man's blood pressure and stopped his facial hair growth.
research Androgenic Alopecia Is Associated With Increased Arterial Stiffness in Asymptomatic Young Adults
Hair loss in young adults is linked to harder arteries.
research Activation of Breast Cancer Cell Proliferation by ROR-Alpha Through Aromatase Promoter
ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.
research Atrophying Squamous Papulous Dermatitis (Degos Disease): Nine Years of Follow-Up
A woman with Degos disease managed her condition for nine years with medications and had two healthy pregnancies, while a separate finding suggests a possible link between female pattern hair loss and high blood pressure.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Hyperandrogenemia in an Ethnically Heterogeneous Cohort of Midwestern United States Diabetic Pregnancies
Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
research Use of Spironolactone in Combination with an Oral Contraceptive in Treatment of Hirsutism
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
research Hyperandrogenism and Pilosebaceous Follicles
High levels of androgens can cause skin issues like acne, hair loss, and excessive hair growth.
research Measurement and Comparison of Various Androgen Levels in Women with Severe Acne, Hirsutism, and Androgenic Alopecia
Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
research Does Finasteride, As Well As Metformin, Improve Insulin Resistance In PCOS?
Both finasteride and metformin effectively treat PCOS by reducing hormone levels and insulin resistance.
research Distribution of Copper, Manganese, Selenium, and Zinc in Occipital and Frontal Hair Zones and Hormonal Profiles in Women with Androgenetic Alopecia
Women with a certain type of hair loss have more copper in the back of their head than the front, and treatment can normalize hair but not copper levels.
research Blood Pressure Levels in Women with Androgenetic Alopecia
Women with androgenetic alopecia may have higher blood pressure levels.
research Diagnostic Approach to Low-Renin Hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
research Impact of Weight Reduction and Oral Contraceptive Pills on Hyperandrogenism
Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.
research Optimal Starting Dose of Clomiphene Citrate for Ovulation Induction in Anovulatory PCOS Women
Choosing the right starting dose of Clomiphene Citrate for ovulation induction in PCOS women is challenging; higher BMI and hormone levels may indicate resistance to the standard dose.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen
Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Association of Hypertension and Hyperaldosteronism with Androgenetic Alopecia in Male Patients: Case control study. (Preprint)
This case-control study investigated the association between androgenetic alopecia (AGA), hypertension, and hyperaldosteronism in a Saudi Arabian male population. Involving 20 males with AGA and 20 healthy controls, the study measured blood pressure and serum aldosterone levels. The results showed no significant differences in aldosterone levels, systolic blood pressure, or diastolic blood pressure between the two groups. The findings do not support the hypothesis that AGA is associated with higher risks of hypertension or hyperaldosteronism, aligning with other studies that question this link. Further research is needed to explore the relationship between AGA and systemic health.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Effect of a combination of ethinylestradiol and desogestrel in adolescents with oligomenorrhea and ovarian hyperandrogenism
The study involved 9 oligomenorrheic adolescent girls with ovarian hyperandrogenism and 8 eumenorrheic controls, treated with a monophasic oral contraceptive containing 0.03 mg ethinylestradiol and 0.150 mg desogestrel for 6 months. The treatment reduced levels of LH, FSH, androstenedione, testosterone, and DHEA-S, while increasing SHBG in both groups. In oligomenorrheic girls, it also decreased ovarian volume and cystic follicles. However, most hormonal levels returned to pre-treatment values 3 months after stopping the treatment, except for SHBG and ovarian volume. Six oligomenorrheic girls reported improved skin and reduced hair growth. Despite its temporary effects, the treatment was effective in managing hyperandrogenism and may help prevent adult micropolycystic ovarian disease.