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    Did you mean 3α-Androstanediol?
    Glossary 3α-Androstanediol

    metabolite of DHT involved in hair follicle regulation

    3α-Androstanediol, also known as 3α-diol, is a metabolite of dihydrotestosterone (DHT), a potent androgen hormone. It plays a role in the regulation of androgenic activity in tissues, including the skin and hair follicles. Elevated levels of DHT are often associated with conditions like androgenic alopecia (male pattern baldness), making 3α-Androstanediol relevant in studies of hair loss and related treatments.

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    1. Clinical Usefulness of Plasma Androstanediol Glucuronide Measurements in Women with Idiopathic Hirsutism* 1987 · 66 citations
    2. 6 Peripheral androgens and the role of androstanediol glucuronide Clinics in endocrinology and metabolism · 1986 · 57 citations
    3. Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate European journal of endocrinology · 1991 · 8 citations
    4. Is 3α, 17β-androstanediol-glucuronide a diagnostic marker in women with androgenic manifestations? Gynecological Endocrinology · 1992 · 3 citations
    5. Verstärkter Haarwuchs unter Langzeittokolyse mit Fenoterol** unter Berücksichtigung von Testosteron, Androstandiol, Cortisol und ACTH* Geburtshilfe und Frauenheilkunde · 1980 · 9 citations
    6. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    7. Elevated serum androstenedione is associated with a more severe phenotype in women with polycystic ovary syndrome (PCOS) Hormones · 2014 · 28 citations
    8. The influence of obesity on Androstenedione to Testosterone ratio in women with polycystic ovary syndrome (PCOS) and hyperandrogenemia Gynecological Endocrinology · 2011 · 15 citations
    9. Scalp hair 17‐hydroxyprogesterone and androstenedione as a long‐term therapy monitoring tool in congenital adrenal hyperplasia Clinical Endocrinology · 2016 · 9 citations
    10. Androstenedione Strength and Conditioning Journal · 1999
    11. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    12. 3α-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats Frontiers in Aging Neuroscience · 2010 · 63 citations
    13. A high-performance liquid chromatography–tandem mass spectrometry assay of the androgenic neurosteroid 3α-androstanediol (5α-androstane-3α,17β-diol) in plasma Steroids · 2005 · 19 citations
    14. Serum 3α-androstanediol-glucuronide is decreased in nonhirsute women with acne vulgaris Fertility and Sterility · 1996 · 10 citations
    15. Effects of non-contingent cocaine on 3alpha-androstanediol. I. Disruption of male sexual behavior Physiology & Behavior · 2019 · 4 citations
    16. A Model for Predicting Polycystic Ovary Syndrome Using Serum AMH, Menstrual Cycle Length, Body Mass Index and Serum Androstenedione in Chinese Reproductive Aged Population: A Retrospective Cohort Study Frontiers in Endocrinology · 2022 · 5 citations
    17. Correlation of Serum 3<i>α</i>-Androstanediol Glucuronide with Acne and Chest Hair Density in Men The Journal of Clinical Endocrinology & Metabolism · 1988 · 51 citations
    18. Female androgenic alopecia. The 3 alpha,17 beta-androstanediol glucuronide/sex hormone binding globulin ratio as a possible marker for female pattern baldness Archives of Dermatology · 1986 · 13 citations
    19. Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens International Journal of Dermatology · 2026
    20. 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism. 1982 · 179 citations
    21. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women Fertility and sterility · 1985 · 142 citations
    22. Androgen Dependence of Hirsutism, Acne, and Alopecia in Women Medicine · 2009 · 105 citations
    23. Effect of Leuprolide and Dexamethasone on Hair Growth and Hormone Levels in Hirsute Women: The Relative Importance of the Ovary and the Adrenal in the Pathogenesis of Hirsutism* The Journal of Clinical Endocrinology & Metabolism · 1990 · 100 citations
    24. Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects Fertility and sterility · 1999 · 75 citations
    25. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    26. Androgen Conjugates: Physiology and Clinical Significance Endocrine reviews · 1993 · 54 citations
    27. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    28. Metformin influence on hormone levels at birth, in PCOS mothers and their newborns Human reproduction · 2009 · 35 citations
    29. PLASMA C19 STEROID SULPHATE LEVELS AND INDICES OF ANDROGEN BIOAVAILABILITY IN FEMALE PATTERN ANDROGENIC ALOPECIA Clinical Endocrinology · 1990 · 32 citations
    30. Clinical relevance of testosterone and dihydrotestosterone metabolism in women ˜The œAmerican journal of medicine · 1995 · 31 citations