August 2026 in “JAMA Dermatology” This study found that upadacitinib significantly improved hair regrowth compared to placebo in adults and adolescents with severe alopecia areata, and demonstrated a positive benefit-risk profile.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
132 citations
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April 2021 in “Stem Cell Research & Therapy” This study found that exosome-incorporated human amniotic membrane scaffolds notably enhanced diabetic skin wound healing in mice, suggesting potential applications for ADSC-derived exosomes in clinical settings.
January 2026 in “Open Science Framework” This scoping review describes the current use of artificial intelligence in alopecia research, highlighting AI's evolution from diagnostic to prognostic applications in dermatology and identifying gaps in multimodal integration and fairness across demographics.
June 2023 in “Journal of Cosmetic Dermatology” This review discusses the transformative potential and challenges of using AI in cosmetic dermatology, highlighting how AI is enhancing diagnostics, treatment personalization, and patient satisfaction while addressing issues such as data quality and ethical concerns in order to ensure responsible and ethical implementation.
July 2022 in “International Journal of Applied Pharmaceutics” This research explored the use of machine learning and deep learning methods to accurately identify alopecia areata in humans by analyzing facial images and demonstrated the potential of these techniques for medical, security, and commercial applications.
18 citations
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August 2021 in “PLoS ONE” This study found that melanocyte progenitor cells are present in human subcutaneous adipose tissue and may differentiate into mature melanocytes, suggesting potential applications in treating skin diseases and rejuvenation.
December 2025 in “World Journal of Stem Cells” This study identified 232 stable proteins in exosomes from human adipose-derived mesenchymal stem cells and suggested a signaling axis that might support future androgenetic alopecia treatments.
January 2024 in “Wiadomości Lekarskie” This study reports that Abelson Interactor 1 (ABI1) regulates androgen receptor transcription in prostate cancer, identifying it as a potential target for new therapies addressing treatment resistance.
February 2026 in “The Journal of Dermatology” This study reports that ritlecitinib 50 mg, with or without an initial loading dose, demonstrated meaningful and sustained efficacy up to 24 months in the Asian subpopulation with severe alopecia areata, showing significant scalp, eyebrow, and eyelash hair regrowth, along with an acceptable safety profile.
70 citations
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July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
2 citations
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September 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This study found that a deep learning model can potentially improve the diagnosis and staging of alopecia areata with high accuracy and reliability.
November 2023 in “Journal of Cosmetic Dermatology” This study highlights the potential of fat injections for treating alopecia, as they may promote hair regrowth, reduce inflammation, and exhibit limited adverse effects, suggesting efficacy and safety in managing the condition.
1 citations
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January 2013 in “MedChemComm” This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.
September 2026 in “Advanced Materials Technologies” In a mouse model study, researchers developed a methacrylated hyaluronic acid-based hydrogel microneedle patch co-loaded with finasteride and a carbon monoxide-releasing molecule for androgenetic alopecia, which showed better hair regrowth and safety compared to traditional treatments, offering an innovative approach with minimized systemic side effects.
52 citations
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May 2011 in “Journal of Neuroendocrinology” This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.
12 citations
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November 2023 in “Medicine” This study used bibliometric analysis to evaluate global research on AI applications in dermatology, identifying 406 relevant papers and highlighting current priorities such as machine learning for wound progression, AI in teledermatology, and applications for skin diseases.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a novel geometric medicine approach, utilizing the N-K Universal Computer, was reported to eliminate aflatoxin contamination and significantly reduce cancer rates across the "Aflatoxin Belt" through precision targeting of harmful fungi while preserving ecological balance, without observed toxicity or resistance.
4 citations
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March 2025 in “The Journal of Dermatology” This study found that in Asian patients aged 12 and older with alopecia areata and significant hair loss, ritlecitinib showed clinical efficacy in improving hair regrowth and eyebrow and eyelash scores over 48 weeks, with an acceptable safety profile observed throughout.
42 citations
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February 2019 in “Circulation” This study observed that DNA damage response (DDR) plays a key role in pressure overload-induced cardiomyocyte hypertrophy, with disruption of the ATM kinase pathway potentially modulating this hypertrophy in mice.
18 citations
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April 2013 in “PLOS ONE” This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.
This study found that a cholesterol-conjugated, cell-penetrating asiRNA targeting the androgen receptor effectively reduced hair loss and promoted hair growth in mouse models of androgenetic alopecia, suggesting potential as a novel treatment.
4 citations
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March 2023 in “Cancer Innovation” This paper discusses the recent advancements and challenges of flexible bioelectronics in personalized health management and cancer therapy, but reports no new studies or results.
2 citations
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January 2024 in “IEEE Access” This study introduces AlopeciaDet, a novel feature fusion technique, using camera images to detect Alopecia Areata with 99.45% accuracy, outperforming existing methods by leveraging CRSHOG and ResNet-50 features.
July 2025 in “The Ewha Medical Journal” This study developed a deep learning model for the automated early detection of androgenetic alopecia using trichoscopic images, and found it demonstrated high accuracy and generalizability in a Korean clinical cohort, achieving a 90% accuracy in external validation.
19 citations
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November 2018 in “Nutrients” This study reports that polyphenols from Annurca apples may safely promote hair growth and protect against chemotherapy-induced alopecia without interfering with chemotherapy regimens.
January 2007 in “Journal of Southwest University” This study identified that the ND1 gene sequence of the Asian black bear's Sichuan subspecies shares high similarity with those of other bear species, raccoons, and Ailurus fulgens.
December 2023 in “Journal of Medicinal Chemistry” In this study, researchers identified compound 30a as a promising topical androgen receptor antagonist that promoted hair growth in mouse models of androgenetic alopecia without noticeable toxicity, suggesting its potential for treating this hair loss condition.
This research highlighted that AI-assisted surgical robots could significantly enhance surgical precision and efficiency by analyzing patient data, making real-time decisions, and automating repetitive tasks, thus potentially improving patient safety and surgical outcomes.
63 citations
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February 2024 in “BMC Psychology” This study reports that emotion recognition technology integrated with intelligent devices is advancing applications to support emotion recognition and interventions, though further research is needed for effective use in dynamic or complex environments.