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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Liposomes could improve how skin care products work but are costly and not very stable.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

New treatments for male hypogonadism are effective and should be personalized.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Hormonal therapies are safe and effective for treating adult women's acne.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

New drug delivery methods can make natural compounds more effective and stable.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Combining laser hair removal with topical eflornithine is recommended for better results in treating unwanted facial hair.

Finasteride effectively treats male hair loss, improving growth and density.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.