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Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Multiple treatments work best for hair loss.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Hormonal therapies are safe and effective for treating adult women's acne.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Zinc can help with some skin problems, but its effectiveness varies depending on the condition.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.