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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Testosterone is crucial for development, growth, and various body functions in mammals.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Lowering testosterone speeds up wound healing in male mice.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Androgens can both increase and decrease hair growth in different parts of the body.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.