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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Androgens can help prevent memory problems caused by apoE4.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

No cure for female pattern hair loss, but various effective treatments exist.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Spironolactone can reduce hair growth in women with hirsutism.