2 citations,
February 2023 in “BMC endocrine disorders” Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.
129 citations,
January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
23 citations,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
3 citations,
March 2022 in “Research journal of pharmacy and technology” Parsley contains compounds that might be good for treating hair loss.
124 citations,
July 2012 in “Archives of Dermatological Research” Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
64 citations,
March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
30 citations,
March 2011 in “Australasian Journal of Dermatology” Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.
24 citations,
March 2003 in “Best Practice & Research Clinical Endocrinology & Metabolism” Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
3 citations,
May 2017 in “Bioorganic & medicinal chemistry letters” New compounds were made that are promising for prostate cancer therapy.
1 citations,
January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
4 citations,
July 2020 in “Research Square (Research Square)” The research helps understand how finasteride works and aids drug development.
105 citations,
January 2009 in “Medicine” Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
26 citations,
January 2020 in “Przegląd Menopauzalny” Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
15 citations,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
6 citations,
June 2017 in “Reproductive Biomedicine Online” Chinese women with PCOS have higher androgen levels, which change with age and weight.
September 2017 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān” Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.
4 citations,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
1 citations,
January 2023 in “Journal of Obstetrics and Gynaecology” High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.
1 citations,
January 2016 in “Journal of Microbial & Biochemical Technology” The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
April 2022 in “Indian Journal of Forensic Medicine & Toxicology” PSA can help diagnose high androgen levels in women.
Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.
15 citations,
April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
14 citations,
April 1978 in “International Journal of Dermatology” Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
197 citations,
January 2019 in “Neuropsychopharmacology” Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
12 citations,
January 2019 in “Journal of Endocrinology” Baicalin may help reduce excessive male hormone levels in PCOS.
April 2012 in “Encyclopedia of Life Sciences” Different genes are linked to various types of hair loss.
January 2011 in “Journal of biological research” Endocrine disruptors may cause early hair loss.
56 citations,
October 2018 in “Journal of The American Academy of Dermatology” Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.