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Flutamide caused damage to male rat reproductive organs and may affect fertility.

New treatments for skin and hair repair show promise, but further improvements are needed.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Found key genes affecting hair loss, immune response, and skin development; more research needed for better treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

PCOS is a long-term condition that needs more research for better understanding and treatment.

The article concludes that different types of hair loss require specific treatments and psychological support is important.

Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.

Certain foods and supplements can help treat skin diseases alongside medication.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

A thorough skin history and examination are essential for diagnosing and treating skin conditions effectively.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.

Platelet-rich plasma (PRP) shows promise in military medicine but its effectiveness varies.

Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.