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Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Colchicine causes rapid hair loss by damaging hair follicles.

Lichen sclerosus et atrophicus is generally not considered precancerous, but there are exceptions.

Colchicine causes hair loss by damaging hair follicles.

Crash dieting can cause hair loss due to severe calorie restriction.

Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.

Lambs fed a liquid diet showed abnormal wool and skin, which improved with more B-vitamins, suggesting a link to B-vitamin deficiency.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

The review suggests limited treatments for common hair loss conditions, with potential for future improvements.

Most skin conditions can be managed with general medical knowledge.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.

Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Herbal remedies can cause adverse effects and need more safety research.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Men with Kennedy disease have less chance of hair loss.

Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.