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The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.

5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

Men with hair loss who take a certain type of medication may experience fewer COVID-19 symptoms.

Dutasteride and finasteride can change hair growth genes, helping treat hair loss.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Taking finasteride pills and using minoxidil lotion together can help grow hair.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Some plant-based products might treat hair loss with fewer side effects than current medications.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.