28 citations
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April 1936 in “Journal of the American Medical Association” This report describes a case where applying fresh aloe vera leaf to roentgen dermatitis resulted in significant skin healing and reduced itching within five weeks.
12 citations
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June 2021 in “Stem Cell Investigation” This study concluded that topical aloe vera promoted faster and better healing of deep second-degree burns in rats compared to mesenchymal stem cells.
10 citations
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January 2022 in “Scholars international journal of anatomy and physiology” This review discusses Aloe Vera's traditional uses and active components but reports no new clinical results, emphasizing its potential benefits from wound healing to hair growth.
This study found that incorporating Aloe vera and celery extract into water or oil microemulsions promoted hair growth in rats, with the water-in-oil formulation showing faster initial results.
2 citations
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September 2025 in “Frontiers in Nutrition” This review reports that various bioactive compounds in Aloe vera demonstrate significant anti-inflammatory, antioxidant, antibacterial, and immunomodulatory effects, supporting its validated use in treating metabolic disorders, gastrointestinal recovery, dermatological conditions, and wound healing due to its nutritional and therapeutic properties.
2 citations
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October 2022 in “Journal of Sustainable Materials Processing and Management” This research found that Nano-Transfersomes containing Vitamin E and aloe vera showed improved permeability and prolonged drug release compared to a marketed formulation, with no skin irritancy observed in mice, potentially offering a sustainable and biocompatible option for psoriasis management.
2 citations
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February 2020 in “Annual Research & Review in Biology” In this animal study, lavender oil, Eruca sativa oil, Aloe vera oil, and sodium carbonate decreased lipid levels and tumor markers in breast cancer models, suggesting potential benefits as adjunctive therapy during chemotherapy.
1 citations
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January 2024 in “Journal of Food Processing and Preservation” This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.
1 citations
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January 2022 in “Journal of Drug Delivery Science and Technology” This study found that a nanotransferosome formulation of finasteride (FI-GO-NTF) in an Aloe vera gel significantly improved scalp permeation and antibacterial activity compared to standard formulations, suggesting safe and effective potential for alopecia areata treatment.
1 citations
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October 2021 in “International journal of pharmaceutics and drug analysis” This study found that a herbal shampoo containing Aloe Vera and essential oils performed better in tests for smoothness, shine, and conditioning compared to a marketed shampoo.
1 citations
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October 2019 in “Proceedings Mulawarman Pharmaceuticals Conference” This study observed that aloe vera serum was comparable to minoxidil in promoting hair growth over 21 days but had no effect on sun protection.
1 citations
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June 2018 in “Pharmaciana” In this study, researchers developed a hair tonic using 7.5% Aloe vera extract and 2.5% licorice extract, finding that the formula with 15% ethanol showed optimum activity by promoting hair growth and increased hair weight in rabbits over 28 days.
1 citations
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July 2017 in “Nusantara bioscience” This study found that supplementation with Aloe vera and Spirulina fusiformis effectively improved the appearance of rabbit skin tissue, particularly in hair texture and skin attributes.
July 2026 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This study found that serum containing keratin extract from chicken feathers combined with Aloe vera showed promising effectiveness for anti-hair loss treatment, with certain combinations outperforming the positive control in measures of hair strength and growth in rabbits.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and tested an eco-friendly herbal hair gel containing extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 excelled in viscosity, spreadability, extrudability, antifungal activity, and stability, making it a promising sustainable alternative to synthetic hair gels.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and tested eco-friendly herbal hair gels using extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 showed optimal viscosity, spreadability, superior antifungal activity, and stability over six months, making it a promising sustainable alternative to synthetic hair gels.
June 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study developed an SLS-free, plant-based anti-dandruff shampoo with favorable characteristics including effective antifungal properties and consumer appeal, suggesting it as a viable alternative to synthetic products.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a plant-based, SLS-free anti-dandruff shampoo with optimal cosmetic properties and antifungal effectiveness, reporting its potential as a safe and biodegradable alternative to synthetic products.
June 2026 in “International Journal of Drug Delivery Technology” This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair cream containing natural ingredients like Jamalgota and Amla was developed and evaluated, with Batch 3 showing promising results in texture, pH balance, spreadability, and stability, suggesting it may be a safe and effective option for managing alopecia.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair cream formulated with natural ingredients like Jamalgota and Neem oil was evaluated for managing alopecia; Batch 3 showed the best performance in texture, stability, and spreadability, with promising results as a safe alternative for promoting healthy hair growth.
March 2026 in “Journal of Drug Delivery and Therapeutics” This review suggests that Aloe vera has potential benefits for various skin conditions by integrating Unani medicinal concepts with contemporary biomedical evidence.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated an herbal shampoo formulated with Amla, Aloe vera, and Bhringraj, finding it to have good cleansing capability, acceptable foaming, suitable pH, and conditioning performance, suggesting it as a stable, safe, and effective alternative to synthetic shampoos for hair and scalp health.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal shampoo made with Amla, Aloe vera, and Bhringraj, finding it to have effective cleansing, foaming, and conditioning properties along with being stable, safe, and irritation-free, suggesting a natural alternative to synthetic options for hair and scalp health.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights aloe vera's role in hair cosmetics, attributing benefits such as scalp soothing, reducing dandruff, and enhancing hair luster to its rich composition, while also noting potential risks like skin irritation and allergic reactions with use.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This overview reports that aloe vera, widely used in hair cosmetics, boasts components that may promote hair health by nourishing hair follicles, soothing the scalp, and enhancing hair strength and luster, although some individuals may experience allergies or skin irritation.
November 2025 in “Universidad Industrial de Santander” In this study, a hair cleansing tonic using Aloe vera and red onion was developed and found effective for promoting hair growth according to sensory tests by 30 panelists in Puerto Wilches, Santander, meeting microbiological safety standards.
September 2025 in “Al-Nahrain Journal of Science” In this research, the authors found that green-synthesized zinc oxide nanoparticles (GS-ZnONPs) exhibited antibacterial activity against Staphylococcus species isolated from alopecia patients, but also showed cytotoxic effects on human dermal fibroblast cells at a 400 mg/mL concentration.
August 2025 in “Tropical Journal of Natural Product Research” This study found that mint leaf and Aloe vera serum together significantly reduced CDK1 expression, which may help prevent chemotherapy-induced alopecia in rats, although only mint serum alone reduced CDC25 expression.
August 2025 in “Academic International Journal of Veterinary Medicine” In this experimental study on rabbits, researchers found that while aloe vera extract did not change the visible wound healing rate, it enhanced histological recovery, promoting early re-epithelialization and minimal inflammation, indicating superior tissue regeneration compared to untreated wounds.