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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Diet changes can protect against harmful environmental effects on fetal development.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Current treatments for alopecia show no significant long-term benefits.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

PEVs improve minoxidil skin penetration, increasing hair growth.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.