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Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Researchers created human hair follicles using a new method that could help treat hair loss.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Some medicinal plants can help heal wounds and may lead to new treatments.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Current treatments for alopecia show no significant long-term benefits.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.