47 citations,
June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
46 citations,
September 2011 in “Movement Disorders” Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
42 citations,
February 1985 in “Journal of the American Academy of Dermatology” Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
41 citations,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
39 citations,
May 2011 in “Movement Disorders” Finasteride may help reduce symptoms in male Tourette syndrome patients.
35 citations,
May 2015 in “Arquivos De Gastroenterologia” Women with PCOS are more likely to have fatty liver disease and worse metabolic health.
32 citations,
January 1997 in “Dermatology” Telogen effluvium is a hair loss condition with acute cases resolving quickly and chronic cases potentially lasting longer, sometimes requiring treatment.
31 citations,
June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
30 citations,
February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
23 citations,
December 2017 in “Scientific Reports” ARL15 is important for fat cell development and the release of the hormone adiponectin.
21 citations,
May 2021 in “Patient education and counseling” Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
20 citations,
July 1990 in “Pediatrics in Review” The four main causes of hair loss in children are fungal infections, pulling out hair, autoimmune hair loss, and stress-related hair shedding.
17 citations,
May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
17 citations,
February 1989 in “Fertility and sterility” Cimetidine did not reduce hair growth in women with hirsutism.
15 citations,
December 2016 in “Revista Da Associacao Medica Brasileira” Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
13 citations,
January 2019 in “Skin appendage disorders” FAPD is a possible diagnosis for hair loss in patients of color and requires multiple evaluations for accurate diagnosis.
13 citations,
January 2014 in “Postępy Dermatologii i Alergologii” Patchy alopecia areata can affect only pigmented hairs, leaving gray hairs untouched.
13 citations,
March 1986 in “Clinical Cardiology” An adult with Kawasaki disease experienced temporary heart failure but recovered without lasting heart damage.
11 citations,
March 2018 in “Anais Brasileiros de Dermatologia” Betamethasone can effectively treat alopecia areata.
11 citations,
January 1998 in “Dermatology” Isotretinoin effectively treated severe acne in HIV-positive women, with improved skin and CD4 counts, but some experienced side effects like skin dryness and hair loss.
10 citations,
January 2018 in “Seminars in Reproductive Medicine” The document concludes that women with PCOS need a comprehensive care model that covers reproductive, metabolic, and psychological health to improve their quality of life.
10 citations,
June 2011 in “Movement Disorders” THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
9 citations,
April 1987 in “International Journal of Dermatology” Stopping the depression medication improved the woman's eyebrow hair loss, and a treatment for a skin condition caused by mites was effective.
8 citations,
February 2003 in “Annals of Neurology” Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
8 citations,
February 1994 in “Archives of Dermatology” Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
7 citations,
June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
7 citations,
April 1987 in “International Journal of Dermatology” Stopping imipramine reduced the woman's hair loss.
6 citations,
January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” An 8-year-old girl with Rapunzel syndrome had a hairball removed from her stomach and intestines and recovered well after surgery.
5 citations,
July 2019 in “Applied statistics/Journal of the Royal Statistical Society. Series C, Applied statistics” Case-only trees and random forests improve predictions of treatment effects in clinical trials.
5 citations,
May 2019 in “Hormone and Metabolic Research” Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.