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Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.

PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Stopping steroids and providing supportive care improved the patient's Cushing Syndrome symptoms and ulcers.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

A woman with type 2 diabetes developed alopecia areata, suggesting a link between the two autoimmune conditions.

Estrogen therapy can reduce skin aging but has cancer risks.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Young men with early hair loss have slightly worse blood sugar and fat levels, suggesting possible health risks and need for monitoring.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.